I am having a hard time with spasms in my legs right now. I don't know I already take baclofen 10mg 3x a day, zanaflex 8mg at night, neurontin 1200mg 2x a day and 1500mg at night, and valium 2mg in morning and 2mg at night.Still seriously I am in severe pain anybody have anything they have tried that has helped seriously I will try anything at this point.Scheduled to go back to Vanderbuilt on November 26. Also another question this is about Tysabri if you have been taken it does it help with muscle spasms?Thanks for any help and hugs to all

Wish I could give you some suggestions, but you're already taking far more medication than I ever did for the spasms (except for the Baclofen dose). Hope you get some relief soon. They're no fun.

Someone will have some good suggestions for you.

I didn't get enough relief with Baclofen @ 30 mg per day like you are on. Once my neuro upped it to 80 mg per day, I had a lot of improvement. I don't know if that is an option for you - not everyone can handle higher doses of Baclofen, but it doesn't bother me. Ask your neuro for ideas on tweaking doses of your meds.

I'm just wondering if this is something that has just come on recently (you said "now"), or if it has been an ongoing problem to the degree it is now? Are you having any other new or worsening of symptoms?

Have you tried a stretching regime of about 15 min per day? Has the weather changed to colder where you are recently? Does soaking in a warm tub help?

Cold weather is the worst for starting up my spasticity and spasms, and I have to be far more vigilant about doing my stretching in the fall/winter. The colder it is, the more I tend to cripple up into a pretzel . . . which leads to spasms. Stretching has always helped considerably.

Cherie

You sound like me recently! I am dealing with these same issues and am on a search for the cause! I have had no relief from Baclofen nor Zanaflex. Valium puts me to sleep and have not tried Neurotin, yet. I recently tried Lyrica and I don't think this is the drug for me! It's a great hallucinagenic and I honestly don't think that's its purpose!! LOL!

I am on Sinemet 25/100 - 2 tablets at night. Also take Klonopin 1 mg at night. This combination seems to help along with some heat 20 minutes on and 20 min off until my legs relax. I also have a hand held massager (HomeMedics! Love it!)

I do some gentle stretching but have found that if I don't apply some heat to my calves and feet (and sometimes even my thigh muscles) I aggravate the situation more than alleviate.

I have tried quinine and it has helped immensely but it was pulled from the market due to adverse reactions. There is a new product that my doc is trying to get approved for me (I don't know what it is called) but it's a form of quinine. I am also more diligent about eating my bananas - potassium!

As for Tysabri, it's not meant for symptom relief. It's a disease modifying treatment. But since I have not been on Ty since 2005, I am not qualified to address your question. I will leave that to those who are on Ty - Riverwild or Natalie or someone who posts on the Tysabri checkin thread would be more experienced in that area!

I am going to a Yoga class tonight that is specifically for people with MS and who have fatigue and spasm issues. I will let you know how it goes!!!

Good luck ...

These spasms have been a ongoing problem. I have started trying to keep a journal of when it happens. I have physical and occupational therapy 3x a week per doctors request but my legs just seem like noodles when I am done with therapy.The spasms are horrible I tried soaking in tub even with dead sea salt as I have heard it was suppose to work. But still no help, the weather here is nice right now but suppose to change in the next few days. I am going to call doctor on Monday and see if possible to up my dose on Baclofen and see if possible a little more would help although I would rather not take medicine at all.I have always been the type I hated taken medicine I would only take it until I was feeling better. Although with this horrible monster I don't have that option or I wouldn't be able to function at all. I just would love any relief at this point. As far as other symptoms my eyes have always been a problem it was how I was diagnosed.Any reflective glare and they don't want to function not to mention the sometimes double vision and excruciating pain behind them. I all at the same time have to be able to function to work so I can't take to much of a sedating drug or I am out like a light. Hugs and thanks for the suggestions