I am still happy to say that since I started LDN, my fatigue has improved,
the pain from the Fribro has lessen.

I am taking less pain meds.

I don't care what some of these research people say, I know what it
is doing for me and for so many of my ms friends.

They should get on this site and talk to us. But, they would be afraid
because we would prove them wrong. All it is, BIG BROTHER won't make a
lot of money on Naltroxane.

It is terrible how money rules our lives and the world. Well one thing I
know is that we all band together here because we know what the true story
is. I never wish anyone ill health, but maybe if more of these people that are
controlling our lives get sick with these certain awful diseases, maybe then
we will have some action on finding a "cure"

Jappy

lady_express_44 has asked me to post this link to an abstract of a paper given at the ECTRIMS conference in mid-September in Germany. The title is "A randomised, placebo-controlled, crossover-design study of the effects of low dose naltrexone on Multiple Sclerosis Quality of Life Inventory (MSQLI54)."

http://registration.akm.ch/einsicht....NMASKEN_ID=900

Thanks agate,

For the "Quality of Life" Inventory study, which was a double blind cross-over clinical trail, makes me wonder how taking their other MS and other medications, during this 16 week trial, could have negated the results of those PWMS who took the LDN?

They usually have criteria for trials. This was a bit bogus, IMO. It's like studying Provigil for 16 weeks when the person is on Amantadine or Ritalin.

How can they compare apples with bananas to pears? We don't know what other medications these trial people on LDN were on, so therefore, the results are not accurate. Also, it takes more than 8 weeks on and then 8 weeks off to get results, from any new added drug (LDN).

Clinical trials are usually a minimum of two years long. This was a cheap imitation of a trial IMO and has no bearing on the outcome of this drugs usage at all. Shame on them for even bothering to do this trial.

Take a 8 week trial on Avonex, Rebif, etc., and see if QOLI is fairly represented. It's impossible. I don't care what drug they tested, the point of the matter is it can't be done in that short amount of time, with no criteria of inclusions and exclusions.
My three cents..

I was dxed 2-08. Due to it being sever 1st line of treatment was/is tysabri. Looks like I've had this for years. Tysabri worked well and I had no lasting damage from 1st attact. I went into a 2nd attack in Nov 08. Again, tysabri worked ok, but I do have minor lasting damage.

Why I am here - very sure I'm in or going into my 3rd attack. In addition, I have a health problem that looks bad. The Drs can't get me well - tried for last 3 mos. Tysabri brings down my immune system too much. I'm set for next infusion on Fri, but doubt I'm well enough for. So, I'm looking at LDN.

What I do not understand is this - if tysabri worked (as a drug that suppresses the immune system) how am I too expect LDN to work as a drug that does the opposite? I know about LDN, but this part I really do not understand.

Any help would be much appreciated.

Pink

Hi Pink! Welcome to NeuroTalk! Here's a good website that can answer most of your LDN questions: http://www.lowdosenaltrexone.org/gazorpa/LDNFAQ.html.

I've been on LDN a little over a year and I've had great success with it. I hope it does the same for you!

Thank you for the info Kitty! I researched LDN a year ago but could not get a Dr to wright it. Hence, I gave up. Now, I'm begging you or anyone for a a Dr. name who will do a phone consult. I'm in the US. Since I'm in an attack, I need to get on LDN as fast as possible. Any help would be appreciated.

Hi Pink, welcome. LDN is not an Immune system booster. What it does is, raise the endorpnine level, which helps the IS to regulate.

Good Luck..

Thanks Sally, I researched LDN last year, but forgot how it worked. Kitty's link helped to refresh my memory. MS cog fog here. I'm going LDN as fast as I can get it written. It looked great last year, and looks even better now.

I just sent you a PM, Pink.

Oh great, more confusion here. It is stated LDN can be taken with other drugs as long as they are not narcotic containing. Is Xanex considered to be narcotic containing. Alprazolam (xanex) is a triazolobenzodiazepine, that is, a benzodiazepine with a triazolo-ring attached to its structure. From my research it looks close, but is not. All of the narcotics on the LDN NO list seem to be pain killers so really hoping I'm right.