Kitty are you in a flare? Or just have the attack of ON? I wish you could see a doctor about this.

If it is going away (the ON), with no relapse, then I guess no steroids would be the answer. I thought you were in a relapse, then the steroids would calm things down.

I can't say Kitty, I'm not a doctor.

Feel better soon, (((((Kelly)))))

Called Dr S for my LDN script renewal and we got to talking. He asked how I was doing...I said Terrific with the exception of my getting older.

I mentioned that I thought LDN was helping me not to age so fast, because it helps me to feel well. He laughed and said "you'd be suprised at how many people are using LDN as an anti aging med. He doesn't recommend it for that, but... I didn't know that, but I'm not surprised.

We both agreed that Endorphins are wonderful things, and he said that there are many miraculous things happening inside our bodies, that we haven't begun to know.

Anyone else feeling the healing and anti aging effects of LDN?

Funny you should mention this, Sal. I read somewhere (wish I could remember where) that LDN is becoming much more popular......especially as a preventive medicine.

I'd continue to take LDN even if it seemed to stop alleviating my MS symptoms. Thank goodness it hasn't but I think it's doing much more good than just helping with my MS.

I wish more people would give LDN a try. I can't imagine what condition I'd be in were it not for LDN.

I have been taking LDN since March 12. I started at 1.5mg for three weeks and then upped to 3mg.

For the last two weeks, my legs have been sooooooo achy, my calves just kill me. I am having trouble sleeping. tossing and turning and putting pillow between knees, but calves still ache. Not sure if it is the LDN or just the MS.

And suggestions?

Should I try to up to 4.5mg or just stay at 3mg?

How much do you all take?

Thanks

You might want to consider going back to the 1.5 dosage for a little while. The same thing happened to me when I tried to go from 3.0 to 4.5. It took several attempts to finally be able to tolerate the 4.5 dosage. That's what I'm on now....4.5......but it took me a while. Everyone is different. You can always try again in a few weeks.

Thank You.

I think I read somewhere, that MS patients with leg spasms/spasiticity may need to stay at 3mg forever.

Is that right? Has anyone else heard this? Anyone here take only the 3mg?

One last question....how long after being on the LDN.....did it take for you to begin feeling better?

Thanks

I stayed on the 3.0 dosage for several months. Each time I'd try to increase my dosage I'd get the spasticity in my legs. Finally I was able to tolerate it. I've read that 4.5 is the optimal dosage so I really wanted to try and see if I could get there. Some people take 3.0 and stay at that level. It's just whatever works for you. We're all different.

I noticed a big difference as soon as I started taking LDN. Even the 1.5 dosage helped me so I was eager to try 3.0. I upped my dosage from 1.5 to 3.0 after only one week.

Hi Daisy,
I started on 1.5 mg, After ten days I went to 3.0 mgs. I have been on that dosage since 12-2008. I tried to up it to 4.5 mgs and found that is the dosage where I get spasticity. So I went back down to 3.0 mgs and have stayed there.

We are all unique in the way we metabolize any medication. I would go back to the 1.5 mgs for a month if I were you, then try again for 3.0 mgs. Our bodies take time to adjust.

I may never try for 4.5 mgs again, or yet I might, down the road. I don't know. I started to see little benefits and improvements on 1.5 mgs, then more on 3.0 mgs.

You don't notice them until you look backward and say, wow, that is getting better or that is gone. It is easier to look after the fact at improvements, than to wake up and say, what is better today?

That was explained to me because I was in a hurry to see benefits, like we all are, when starting a new medication.

Take it at bedtime. It has a half life of 4 hours (it only works for about the first few hours of sleep. If you stay awake too long after dosing it may not work that night as it is supposed to. JMO

Sally, about that feeling of anti-ageing, I don't know to tell the truth. I do feel that LDN gives us a good, well-being-feeling. It is a mood lifter and pain reliever too.

I don't feel my age. But I wish I could do many things I did in my youth, like dance all night, skate, climb hills, keep going for 18+ hours a day, non-stop, etc. But that is the disease.

I do feel so much better since on LDN, I have many improvements so I can't complain.

Maybe complaining is a sign of age? Maybe we are just all young kids at heart.

Here is Wiki stuff.

What are Endorphins?

Endorphins are endogenous opioid polypeptide compounds. They are produced by the pituitary gland and the hypothalamus in vertebrates during exercise, excitement, pain, consumption of spicy food and orgasm, and they resemble the opiates in their abilities to produce analgesia and a feeling of well-being.

Endorphins work as "natural pain relievers."

The term "endorphin" implies a pharmacological activity (analogous to the activity of the corticosteroid category of biochemicals) as opposed to a specific chemical formulation. It consists of two parts: endo- and -orphin; these are short forms of the words endogenous and morphine, intended to mean "a morphine-like substance originating from within the body."

The term endorphin rush has been adopted in popular speech to refer to feelings of exhilaration brought on by pain, danger, or other forms of stress, supposedly due to the influence of endorphins.

When a nerve impulse reaches the spinal cord, endorphins are released which prevent nerve cells from releasing more pain signals. Immediately after injury, endorphins allow animals to feel a sense of power and control over themselves that allows them to persist with activity for an extended time.

What is Naltrexone and Low Dose Naltrexone? See below link:

http://en.wikipedia.org/wiki/Naltrexone

PS: LDN increases are own Endorphins, while we sleep.

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