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-   -   Another Mestinon Question (https://www.neurotalk.org/myasthenia-gravis/108469-mestinon-question.html)

AnnieB3 11-20-2009 08:27 PM

Well, "playing with the dosage" is okay as long as you don't take huge jumps in it!!!! Geez. Sometimes these neuros, even the experts, act like Mestinon is a placebo. I'm glad you will be sensible, Kendra. An MG crisis is a whole new ball game and you don't want to end up with one. It can take longer to bounce back from that and it involves so many more invasive treatment options.

PMCPMC 11-21-2009 01:39 AM

Quote:

Originally Posted by PMCPMC (Post 591553)
WITHOUT PRED TO REDUCE IMMUNE SYSTEM AMOUNT OF MESTINON IS DIRECTLY LINKED TO ACTIVITY LEVEL.
If I shower and dress and do some light house chores then 120 at 7:00am may needed to be suppemented at 7:50am with 120mg more as mestinon sodium ions have been used up by the activity hence so side effects .determined only by weakness feeling in my neck which drops to my chest or I CANNOT LIFT MY ARMS ABOVE MY HEAD.
Don't take it and you put all the surrrounding muscles under pressure in chest ,shoulders back which try to step in and take over from the neck muscles.
Soem of our experts will be able to tell you from the medicine bible what the safe upper limits are per day in mg or gms .
Moving slowly up until overdose signs start as muscle twitch and eye twitch in my case.
I am taking 60mg pred per day which has not kicked in to reduce the antibody occupation of my muscle receptors,according to neuro doctor.
takes four to six weeks from start.
Significant to know mestinon without pred or something to reduce immune system according to neuro doctor will cause long term damage to the receptors as battle rages to occupy the receptors between yoyr immune antibodies and the synthetic sodium ion replacement in mestinon

synthetic sodium ion replacement in mestinon THIS WAS TO SIMPLIFY THE EXPLANATION NOT FACTUAL AS YOU KNOW ANNE AS THE REAL SITUATION IS MORE COMPLJCATED BUT IT WAS TO HIGHLIGHT THE NEED FOR A TWO PRONG ATTACK ACCORDING TO MY NEURO DOCTOR.
AS IT AN AUTO IMMUNE CONDITION THAT MUST BE ACCORDING TO HIM THE FIRST LINE OF ATTACK ON THE CONDITION TO REDUCE THE AUTO IMMUNE RESPONSE AND USE MESTINON ETC ONLY IF NECCESSARY.I WILL LEARN TO BE MORE CAREFUL WITH MY WORDS IN FUTURE MAKING SURE I REFER TO THE APPORPEIATE RESEARCH ARTICLE .
i HAVE READ ONE SOMEWHERE ,I WILLTRY AND FIND IT AGAIN.SORRY AGAIN FOR ANY CONFUSION


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