Hey annie- I had a question. You know that drug reaction vetween a neuromuscular disorder and accutane/ isotretinoin? The site u sent me? Could that of caused permenent muscle damage? Could I now suffer from that? I feel there are muscles in my body that are very deteriorated yet unsure if that's mg. Thanks

I would say that if you are WEAKER and sicker now than you were when you started, then you are in trouble.

Accutane is known to be a cause of toxic myopathy.
http://neuromuscular.wustl.edu/mother/myotox.htm

Many of the papers on the net require membership and payment to view. But you can Google Toxic myopathy and you may find more.

This abstract (the only part that is "free") suggests that toxic myopathies may improve if the trigger is removed.
http://www.mdconsult.com/das/article...?issn=07338619

If you do not show positive antibodies typical of MG patients, you should consider a toxic cause. MG is very uncommon in young males. Most of the epidemiologic studies do not show it in your age group for males.

Accutane is one of the most toxic drugs available today. It has almost been removed from sale, more than once.

Here is a link to the official FDA medwatch reports thru doctors.
http://patientsville.com/medication/...de_effects.htm
These reports are pretty clear because the patients are young and don't use other drugs. (in older patients on several medications the reports may be less easy to interpret).
Notice 52% demonstrated severe side effects.

I think you can find more with more time searching.

I have seen some dermatologists prescribe this product for mild to moderate acne...and the patients in general liked it and tolerated it well-- it works well too.
http://en.wikipedia.org/wiki/Nicomide
I don't have experience with the topicals, and only saw the oral tablet.

Tyson, I don't know the answer to your questions cause I'm not a psychic! You have to have your docs run tests, etc. It is in the realm of possibilities that the drug is doing damage to your body. Only time will tell if it's permanent or not. The body has extraordinary healing abilities BUT only if you take away what is making it toxic.

Listen to Mrs. D. She absolutely knows what she is talking about. And I completely agree that you could be in real trouble.

I was wondering if what you have on your face, the redness you describe, is rosacea. Has anyone ever said anything about that to you? Maybe it's acne but I think it's time to think outside the box.

http://www.rosacea.org/index.php

http://www.mayoclinic.com/health/rosacea/ds00308

It's worth bringing up to, perhaps, a 2nd opinion dermatologist.

You haven't had much experience with drugs. They can help you but they can hurt you too. Mrs. D. had given you LOTS of great advice about acne, among other things. I truly don't believe Accutane is worth the risk to your health. But it's your decision.

I hope you don't have any damage. But if this drug is causing you to be weak, it doesn't take a doctor to figure out what the ramifications of that are.

Hang in there!!!

Annie