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Old 01-23-2012, 09:13 PM #1
Stellatum Stellatum is offline
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Default iodinated contrast agents

Iodinated contrast agents (for use in CT-scans) are on the list of drugs myasthenics shouldn't use. Here's a new study that shows that they raise the risk of thyroid problems significantly. Since MG patients are prone to Graves' disease anyway, it's something to keep in mind.

http://www.medscape.com/viewarticle/757345

When I went to have my thymus scanned, the neurologist and the radiologist couldn't agree whether the contrast agent was necessary, had never heard that iodinated contrast agents are dangerous for MG patients, and didn't know if a Graves' patient could tolerate the iodine anyway. So, now we can add a fourth thing they didn't know to the list. I spent three hours at the radiologist's that day, and all I got out of it was a huge caffeine-withdrawal migraine because I was fasting in my johnnie the whole time they were inconclusively arguing. Not my favorite patient memory. In the end I announced I was going home, and they could call me when they figured it all out.

Abby
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Old 01-24-2012, 09:15 AM #2
4-eyes 4-eyes is offline
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Please be careful when you say a drug "shouldn't" be used. Many people with MG must and do use iodine agents as well as other drugs with absolutely no issues. There are just quite a few drugs that need to be used "with caution" or sometimes with some pre-medication for people with MG.

When one goes out to make a list of things to be avoided, you must be careful to balance the value of the drug in general with the possible complications of the individual. I guess what I'm saying is do your research when possible, so you and your doctor can make the best informed decision.

Looking back at my reboot, I had so many drugs it's unbelievable. IV ativan for nausea, which caused no issues at all for me. OTOH, IV magnesium, which HAD to be given due to a huge imbalance, caused MAJOR issues for a whole day. It was pretty impressive! The list goes on and on. However, with each drug came thoughtful consideration, as well as a back up plan in case of issues.

I, btw, cannot tolerate iodine agents, but not because it causes problems iwth MG--just because I'm allergic!

Good luck.
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Old 01-24-2012, 09:19 AM #3
Stellatum Stellatum is offline
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Thanks, I think that's exactly right. Everyone, take note!

Abby
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Old 01-24-2012, 10:43 AM #4
Brennan068 Brennan068 is offline
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Quote:
Originally Posted by Stellatum View Post
Iodinated contrast agents (for use in CT-scans) are on the list of drugs myasthenics shouldn't use. Here's a new study that shows that they raise the risk of thyroid problems significantly. Since MG patients are prone to Graves' disease anyway, it's something to keep in mind.

http://www.medscape.com/viewarticle/757345

When I went to have my thymus scanned, the neurologist and the radiologist couldn't agree whether the contrast agent was necessary, had never heard that iodinated contrast agents are dangerous for MG patients, and didn't know if a Graves' patient could tolerate the iodine anyway. So, now we can add a fourth thing they didn't know to the list. I spent three hours at the radiologist's that day, and all I got out of it was a huge caffeine-withdrawal migraine because I was fasting in my johnnie the whole time they were inconclusively arguing. Not my favorite patient memory. In the end I announced I was going home, and they could call me when they figured it all out.

Abby
Take a look at the list that I sent to Annie http://neurotalk.psychcentral.com/thread162413-2.html

Iodinated Contrasting agents is on the list as a "potential problem". Also Magnesium given at doses to raise serum Mg level is frequently reported as a problem.

As always, the doctor and you need to weigh the immediate needs vs the longer term potential problems/benefits.
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