Myasthenia Gravis For support and discussions on Myasthenia Gravis, Congenital Myasthenic Syndromes and LEMS.


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Old 02-12-2012, 08:06 PM #1
Geode Geode is offline
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Join Date: Feb 2011
Posts: 91
10 yr Member
Geode Geode is offline
Junior Member
 
Join Date: Feb 2011
Posts: 91
10 yr Member
Default Also the VGKC antibodies

Besides this new one, the AChR's and MuSK, there's also the VGKC (potassium ion channel) antibodies that can be associated with MG.

"Patients with VGKC antibodies may have associated myasthenia gravis with or without acetylcholine receptor antibodies"

http://www.pnseuronet.org/vgkc.php

This is not the same thing as VGCC antibodies associates with LEMS.

This test protocol page from Mayo clinic mentions these as well as others:

http://www.mayomedicallaboratories.c...Overview/83370


Here is a video of a woman I "know" who tested positive for VGKC antibodies. With the connection to the potassium channels, she was thinking an autoimmune form of periodic paralysis, but I know she's been looking into MG more recently, as PP episodes usually occur during a rest period AFTER exercise, while according to Annie, fatiguable weakness is the hallmark of MG.

http://www.youtube.com/watch?v=QfuzY...eature=mh_lolz
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