FAQ/Help |
Calendar |
Search |
Today's Posts |
|
Myasthenia Gravis For support and discussions on Myasthenia Gravis, Congenital Myasthenic Syndromes and LEMS. |
Reply |
|
Thread Tools | Display Modes |
08-13-2012, 11:16 AM | #1 | |||
|
||||
Member
|
Does mestinon cross the blood/brain barrier?
I was wondering if it has any effect on the central nervous system. The drugs to improve cognition with Alzheimer's are acetylcholinesterase inhibitors. So I was wondering if mestinon also helps with cognition problems. Any ideas on this?
__________________
Celeste |
|||
Reply With Quote |
08-13-2012, 11:35 AM | #2 | ||
|
|||
Member
|
Yes, it can cross the blood/brain barrier. No, it is not supposed to. Nobody has really researched it in depth, but it seems to be stress related - if you're under a lot of stress it can. There is some evidence that Gulf War Syndrome is related to this.
|
||
Reply With Quote |
08-13-2012, 10:35 PM | #3 | ||
|
|||
Member
|
From what I've read, very little of it does. There was a study done several years ago showing that we have less acytocholine in the brain and one of the conclusions was that a trial should be conducted using a drug that does cross the blood/brain barrier, but I couldn't find whether the follow up study was ever run.
|
||
Reply With Quote |
Reply |
|
|
Similar Threads | ||||
Thread | Forum | |||
Technology to Cross the Blood Brain Barrier | Parkinson's Disease | |||
Blood-Brain Barrier | Parkinson's Disease | |||
Essential oils can cross the BBB -blood brain barrier.. | Parkinson's Disease | |||
Blood Brain Barrier | Parkinson's Disease | |||
Blood Brain Barrier | Multiple Sclerosis |