Originally Posted by southblues

My car wouldn't start. It had a good battery. The wires were good. The engine was good. But there was something in the connection. Gunk.

Myesthenia gravis is a disorder in which the receptors for the neurotransmitter are blocked.

So we have the battery -- the nervous impulse and the release of the acetylcholine.

We have the engine -- the muscles.

The acetylcholine just can't attach to the receptor sites on the muscle.

So we lack a connection. There is gunk in the connection. (antibody)

Mestinon causes the acetycholine that is released to stay around longer. This allows the receptor sites that aren't blocked to have a better chance at getting a signal.