Why does Mestinon favor some muscles yet ignore others?

jana · 10-30-2012, 09:39 AM

Quote:

Originally Posted by southblues

I really wish that I could understand the asymmetry of this problem. Why is my right side so much worse than my left? I can understand that eyelids are inherently weaker than legs and therefore would be more problematic. I just can't understand the asymmetry. I can't understand why my right eyelid closes, my right eye is blurry, my right leg is weak, etc.

Celeste, I actually UNDERSTAND (or I "think" I do) why my right eye is "wonky". I am right-handed, have migraines on the right side, and my right eye is dominant. What I DON'T understand is why my LEFT leg is the one that drags (mostly when I'm in exacerbation).

C-R-A-Z-Y disorder for people obsessed with logic (me, a former math teacher).

SoftTalker · 10-30-2012, 12:33 PM

Quote:

Originally Posted by southblues

I really wish that I could understand the asymmetry of this problem. Why is my right side so much worse than my left? I can understand that eyelids are inherently weaker than legs and therefore would be more problematic. I just can't understand the asymmetry. I can't understand why my right eyelid closes, my right eye is blurry, my right leg is weak, etc.

And, my MG is just the opposite.

Left eye droops much more than right one, left leg is weaker.

However, when left eye is closed during eye exam(s) doc(s) often notice my right eye starts to droop.

Very interesting.......

south, I too have asked these very questions myself and asked doctors.

So far, no answers.

I think "they" are still working on curing the common cold!

AnnieB3 · 10-30-2012, 06:09 PM

SoftTalker, It's called "enhanced ptosis" or the "see-saw effect."

http://archneur.jamanetwork.com/arti...ticleid=580026

If you have a dominant eyelid droop, pull up on that eyelid and then watch as that one goes up and the other goes down! They can go back and forth like that for awhile. You can do that if you look sideways at something too, which I often notice if I lie in bed and look at the TV from one side.

It's a compensatory effect, not unlike how our other muscles operate!

Annie

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