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Old 06-13-2013, 12:15 PM #1
Stellatum Stellatum is offline
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Join Date: Feb 2010
Posts: 1,215
10 yr Member
Stellatum Stellatum is offline
Senior Member
 
Join Date: Feb 2010
Posts: 1,215
10 yr Member
Default Lrp4 antibodies and 3,4-dap

Here are articles suggesting that people who have tested negative for AChR antibodies and MuSK antibodies might have low-density lipoprotein receptor-related protein 4 antibodies. http://www.ncbi.nlm.nih.gov/pubmed/21387385 and http://www.ncbi.nlm.nih.gov/pubmed/22158716 and http://archneur.jamanetwork.com/arti...icleid=1150052

One of these articles said that people with Lrp4 antibodies don't respond to Mestinon. I know that people with MuSK antibodies often don't respond well to Mestinon, either. There's new evidence that MuSK MG patients respond to 3,4-Dap, which is also used in CMS.

I don't think there's much chance my neuro would try me on 3,4-Dap. I tested negative for MuSK, too. I'm just thinking that if 3,4-Dap helps people who have MG but don't respond to Mestinon, who knows--maybe it will help me. Any thoughts?

Abby
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