Myasthenia Gravis For support and discussions on Myasthenia Gravis, Congenital Myasthenic Syndromes and LEMS.


advertisement
Reply
 
Thread Tools Display Modes
Old 08-31-2013, 07:22 PM #1
BARBARA356's Avatar
BARBARA356 BARBARA356 is offline
Junior Member
 
Join Date: Feb 2009
Location: SC
Posts: 86
15 yr Member
BARBARA356 BARBARA356 is offline
Junior Member
BARBARA356's Avatar
 
Join Date: Feb 2009
Location: SC
Posts: 86
15 yr Member
Default Methotrexate

Has anyone just stopped methotrexate? If so can it cause symptoms?
BARBARA356 is offline   Reply With QuoteReply With Quote

advertisement
Old 08-31-2013, 08:08 PM #2
southblues's Avatar
southblues southblues is offline
Member
 
Join Date: Jul 2012
Location: Georgia USA
Posts: 818
10 yr Member
southblues southblues is offline
Member
southblues's Avatar
 
Join Date: Jul 2012
Location: Georgia USA
Posts: 818
10 yr Member
Default

I have never taken it. I just looked it up. It seems like they really got out the big guns with you. Have you tried milder treatments?
__________________
Celeste
southblues is offline   Reply With QuoteReply With Quote
Old 08-31-2013, 08:14 PM #3
BARBARA356's Avatar
BARBARA356 BARBARA356 is offline
Junior Member
 
Join Date: Feb 2009
Location: SC
Posts: 86
15 yr Member
BARBARA356 BARBARA356 is offline
Junior Member
BARBARA356's Avatar
 
Join Date: Feb 2009
Location: SC
Posts: 86
15 yr Member
Default

Quote:
Originally Posted by southblues View Post
I have never taken it. I just looked it up. It seems like they really got out the big guns with you. Have you tried milder treatments?
Yes, I think I have tried them all, this was a last resort
BARBARA356 is offline   Reply With QuoteReply With Quote
Old 08-31-2013, 09:12 PM #4
southblues's Avatar
southblues southblues is offline
Member
 
Join Date: Jul 2012
Location: Georgia USA
Posts: 818
10 yr Member
southblues southblues is offline
Member
southblues's Avatar
 
Join Date: Jul 2012
Location: Georgia USA
Posts: 818
10 yr Member
Default

Is it causing problems? If you get off of it, won't your MG get worse?
__________________
Celeste
southblues is offline   Reply With QuoteReply With Quote
Old 09-01-2013, 09:47 AM #5
anon6618
Guest
 
Posts: n/a
anon6618
Guest
 
Posts: n/a
Default

I've been on it for almost a year. It worked for my MG: not as much as a nice high dosage of prednisone, but it worked better than all the others - which all didn't do a thing (azathioprin, cellcept, etc).
I just stopped cold turkey, had to because it already caused irreverisble damage to my liver, and is not like prednisone where you cannot stop just like that.

I did not have any problems, though after a few weeks my MG got a bit more room to play around. But just to compare: 2,5 mg less of the prednisone is much more MG problems than stopping the MTX 25 mg I took (injected) weekly. For me anyway! I do not know or can predict what will happen to you - just so you know.

Are you on any other drugs? Because if the MTX is the only one you use, and it works good for you, fat change stuff will get worse if you stop. Again; no diagnosis or whatever.

Why do you have to stop?
  Reply With QuoteReply With Quote
Old 09-01-2013, 01:29 PM #6
BARBARA356's Avatar
BARBARA356 BARBARA356 is offline
Junior Member
 
Join Date: Feb 2009
Location: SC
Posts: 86
15 yr Member
BARBARA356 BARBARA356 is offline
Junior Member
BARBARA356's Avatar
 
Join Date: Feb 2009
Location: SC
Posts: 86
15 yr Member
Default Stopping Methotrexate

I stopped because I was worried about the damage it can cause. I am having a lot of trouble with my ankles this week.
BARBARA356 is offline   Reply With QuoteReply With Quote
Old 09-01-2013, 05:06 PM #7
southblues's Avatar
southblues southblues is offline
Member
 
Join Date: Jul 2012
Location: Georgia USA
Posts: 818
10 yr Member
southblues southblues is offline
Member
southblues's Avatar
 
Join Date: Jul 2012
Location: Georgia USA
Posts: 818
10 yr Member
Default

You (hopefully with your doctor) need to look at risks versus benefit. All these drugs we take are a bit hazardous. We are taking risks when we take them. You and your doctor need to weigh the risks against the benefits and look at your quality of life.

What will your life be without drugs? Will you even live?

Is there something else you can take that is safer?

For my own life, I don't really want to keep going if I am totally incapacitated. If I can't keep some normalcy to my life, then I will take high risks with drugs that might help.

My sister, on the other hand, is perfectly content to sit on the couch watching TV letting other people wait on her hand and foot.

You just have to weigh the costs and what you get out of them.

Good luck with all this.
__________________
Celeste
southblues is offline   Reply With QuoteReply With Quote
"Thanks for this!" says:
gr8ful (09-02-2013)
Old 09-02-2013, 06:34 AM #8
anon6618
Guest
 
Posts: n/a
anon6618
Guest
 
Posts: n/a
Default

Quote:
Originally Posted by BARBARA356 View Post
I stopped because I was worried about the damage it can cause. I am having a lot of trouble with my ankles this week.
What about your ankles? Are you sure it is caused my the MTX?
Did you talk about this with your doc?

There are risks, but not more than any other immune suppressant has. I had the unfortunate luck it caused irreversible damage in only a few months. But there are a lot of people who use it without any problems whatsoever. For years!
You just have to be very careful and check your blood regularly and take folic acid.

Anyway, if you do not have severe MG problems without it, it's up to you.
  Reply With QuoteReply With Quote
"Thanks for this!" says:
cait24 (09-02-2013)
Reply

Thread Tools
Display Modes

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off


Similar Threads
Thread Thread Starter Forum Replies Last Post
SAPHO and Methotrexate Koala77 General Health Conditions & Rare Disorders 8 03-06-2014 06:26 PM
methotrexate questions knittenkitten Medications & Treatments 0 11-08-2010 10:25 AM
Methotrexate DAY1 Medications & Treatments 9 08-09-2008 07:36 AM
Your exerience with methotrexate DAY1 Multiple Sclerosis 4 03-28-2008 11:00 PM
Need Advice About Methotrexate kingrex Multiple Sclerosis 4 12-17-2006 02:48 AM


All times are GMT -5. The time now is 09:37 AM.

Powered by vBulletin • Copyright ©2000 - 2024, Jelsoft Enterprises Ltd.

vBulletin Optimisation provided by vB Optimise v2.7.1 (Lite) - vBulletin Mods & Addons Copyright © 2024 DragonByte Technologies Ltd.
 

NeuroTalk Forums

Helping support those with neurological and related conditions.

 

The material on this site is for informational purposes only,
and is not a substitute for medical advice, diagnosis or treatment
provided by a qualified health care provider.


Always consult your doctor before trying anything you read here.