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Old 11-14-2014, 02:53 AM #1
Plantagenet Plantagenet is offline
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Location: Nottingham, UK
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Plantagenet Plantagenet is offline
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Join Date: Jul 2014
Location: Nottingham, UK
Posts: 38
8 yr Member
Default Fatigue in myasthenia gravis: is it more than muscular weakness?

I found this study just recently though it is from 2012 I think, so I don't know if it's been linked to here before but here it is any way.

http://www.biomedcentral.com/1471-2377/13/132


John
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AnnieB3 (11-16-2014), juliejayne (11-16-2014), Psychitect (11-17-2014)

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Old 11-15-2014, 06:39 PM #2
AnnieB3 AnnieB3 is offline
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AnnieB3 AnnieB3 is offline
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Thanks, John.

There have been a few studies in the are of fatigue (sleepiness) in MG. I liken it to metal fatigue. When a bridge, for example, has too much metal fatigue, it collapses.

In MG, it seems that when the general weakness becomes to great, our mind says, okay, time to sleep now! The body has mechanisms like that in place for a lot of things. For example, if you don't drink enough water, the body concentrates your urine by kicking in more ADH to retain it.

I thought it was a very well done study, and they were honest about its limitations. I have to wonder what other factors might come into play, such as a lack of sleep, insufficient nutrients, other conditions, etc.

I appreciate you putting this study up here!

Annie
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