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fluoroquinolone eye drops?

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Old 02-25-2018, 07:05 AM   #1
Join Date: Feb 2011
Posts: 243
Default fluoroquinolone eye drops?

I had eye surgery 5 days ago, and so have been on Besivance eye drops for 8 days. Supposed to stay on it for at least 2 more weeks. Besivance is the trade name for besifloxacin, a fluoroquinolone.

I am on pyridostigmine, mestinon. Normally works pretty well. But the last week, not as good as usual.

Not seeing or reading very well at the moment, understandably. But aren't fluroquinolones one of the 'don't do it' drugs for MG? Even tho these are eye drops, the drug does go systemic, a little bit. Enough that they make note of it doing so. Many eye drops do.

Also wondering, if it is something that could be working against me, if that might be why that eye's pupil is remaining noticeably more dilated than the other eye (which is normal) and not reacting to light as well (tho it does, just more weakly). Really nothing in the surgery that was done that should have caused that, they use massive amounts of dilating drops so the doc hasn't been worried yet, says some people just take longer, and give it another day, but it's now been 5 and it seems to have stalled at twice the size of the normal eye.

So, could Besivance, besifloxacin, a fluoroquinolone, be affecting how well the mestinon works and maybe how well the pupil of that eye works?
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AnnieB3 (03-03-2018)
Old 03-03-2018, 09:46 PM   #2
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Join Date: Feb 2009
Posts: 3,174

Some people are "ok" on the quinolones. The FDA has put a stronger warning on them for MGers. Since you need the drops, take each day at a time. If your breathing, swallowing, or generalized symptoms become worse, I'm sure they can find a different drop for you.

The dilation drops contains Atropine, which does the opposite of Mestinon. But your eyes should not be dilated this long. My eyes are dilated longer than most people, but not for days. The eye doctor obviously doesn't realize that "massive amounts" of those dilation drugs are not a good idea in MG! I always ask for less that what other have.

How are you doing now?

All of those eye drops can affect MG. Some people do worse on them than others. If you are still not doing well, you should speak to the prescribing doctor again.

I'm sorry this is affecting you. I hope the surgery went well.

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besivance, drops, eye, fluoroquinolone, normal

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