Myasthenia Gravis For support and discussions on Myasthenia Gravis, Congenital Myasthenic Syndromes and LEMS.


advertisement
Reply
 
Thread Tools Display Modes
Old 03-12-2019, 08:26 PM #1
susan_mela susan_mela is offline
Junior Member
 
Join Date: Feb 2019
Posts: 18
5 yr Member
susan_mela susan_mela is offline
Junior Member
 
Join Date: Feb 2019
Posts: 18
5 yr Member
Default IVIG for MG leading to SPS symptoms.... or is it plain SPS?

Has anybody had the experience of IVIG for MG causing Stiff Person Syndrome symptoms through raised GAD65 Ab (antibodies)? I admit to never having been the most physically relaxed person, even before IVIG, and many of the "typical patient profile" descriptions have long been true, but my spasms have gotten markedly worse since starting IVIG treatment a year ago for Myasthenic crisis.

I'm starting on Baclofen after Flexoril was a big 0. Getting another antibody test at the end of this IVIG cycle.

Has anyone had this happen *from* IVIG? Does anyone know what the deciding factor is in telling if one is causing the other, or if I do truly have SPS in adddition to MG?
susan_mela is offline   Reply With QuoteReply With Quote

advertisement
Old 03-13-2019, 02:54 AM #2
kiwi33's Avatar
kiwi33 kiwi33 is offline
Grand Magnate
 
Join Date: Jan 2015
Location: Sydney, Australia.
Posts: 3,093
8 yr Member
kiwi33 kiwi33 is offline
Grand Magnate
kiwi33's Avatar
 
Join Date: Jan 2015
Location: Sydney, Australia.
Posts: 3,093
8 yr Member
Default

Stiff Person Syndrome is a known side-effect of the presence anti-GD65 antibodies.

NHSGGC : Anti-GAD65 Antibodies associated with Stiff Person Syndrome
__________________
Knowledge is power.
kiwi33 is offline   Reply With QuoteReply With Quote
Old 03-13-2019, 09:49 AM #3
susan_mela susan_mela is offline
Junior Member
 
Join Date: Feb 2019
Posts: 18
5 yr Member
susan_mela susan_mela is offline
Junior Member
 
Join Date: Feb 2019
Posts: 18
5 yr Member
Default SPS caused by IVIG for MG?

Yes, indeed. Thank you, kiwi33. I am wondering if other MG patients on forum have had SPS result from IVIG treatment. I know that can happen. It is currently unclear which came first in my case. Was the SPS present in lesser form before I started on IVIG? It has certainly ramped up since starting the treatment. This is all such a mystery, since IVIG is also used to treat SPS.

Quote:
Originally Posted by kiwi33 View Post
Stiff Person Syndrome is a known side-effect of the presence anti-GD65 antibodies.

NHSGGC : Anti-GAD65 Antibodies associated with Stiff Person Syndrome
susan_mela is offline   Reply With QuoteReply With Quote
Reply

Tags
ivig, person, sps, starting, symptoms

Thread Tools
Display Modes

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off


Similar Threads
Thread Thread Starter Forum Replies Last Post
Just plain tired CRPSsongbird Reflex Sympathetic Dystrophy (RSD and CRPS) 6 06-22-2013 01:28 AM
worsening symptoms with IVIg? violet4941 Myasthenia Gravis 12 02-06-2012 03:12 PM
Symptoms Leading to MG? GI6607 Myasthenia Gravis 5 03-29-2008 10:36 PM
Have you ever been just plain fed-up with Doctors? Quahog Chronic Pain 12 11-17-2006 11:50 AM


All times are GMT -5. The time now is 01:31 PM.

Powered by vBulletin • Copyright ©2000 - 2024, Jelsoft Enterprises Ltd.

vBulletin Optimisation provided by vB Optimise v2.7.1 (Lite) - vBulletin Mods & Addons Copyright © 2024 DragonByte Technologies Ltd.
 

NeuroTalk Forums

Helping support those with neurological and related conditions.

 

The material on this site is for informational purposes only,
and is not a substitute for medical advice, diagnosis or treatment
provided by a qualified health care provider.


Always consult your doctor before trying anything you read here.