If you respond to the epsom salts, do them once a day for at least a week. The magnesium in them opens up small blood vessels to improve circulation there and also they block pain signals from the NMDA pain receptors.

It is safe, inexpensive and easy to use epsom salts as a soak, as long as you don't use hot water.

Look at what you are eating. Too much sugar or carbs, or MSG in processed food (including restaurant food), or histamine containing foods can cause nerve problems for some people.
Some react to hot sauces which are nightshades. Avoid hot sauces, chilis , paprika for 2 weeks if you eat them alot. You might be surprised at the improvements you may have.

There is a histamine thread in the subforum at the PN forum here. Search "histamine" on page one there and I have some links you can read.

I will absolutely try epsom salt baths thanks for the advice.

I do eat a lot of sugar, possibly carbs too, also some histamine foods. I could try with antihistamines and to cut it.

What is bad is that I can't sleep well. Spasms wake me up and sometimes won't subside for an hour. I am very tired and there is anemia too.
I am worried that spasms are mostly in that thumb muscle the rest are minor and rare and move around. Only this one is focal but strong enough to bother me.

Typical antihistamines do not really work on food allergies or food induced histamine.

The H2 blockers work better on food issues. This is Zantac, Pepcid and Tagamet. Allergists use these for food reactions.

Another thing that works on food problems is Sod. Bicarbonate.
AlkaSeltzer Gold or the plain tablets. This blocks histamine receptors and can reduce chronic pain. No more than 3 times a day. But avoiding the triggers is the best way to do this rather than supplements after the fact..

If you are engaging in some exercise to stress your hand, like boxing, making fists, or grasping some tool with stressful force, that has to stop. Some yoga positions may stress the hand and palms.. Are you using some squeeze balls or hand energizers?
If so stop them.

Baby yourself for at least a month. See if things change.

You know, sometimes these things resolve themselves on their own.

Omg, I do cardio kick-boxing and boxing, at least I did up until a week ago! But I loved it... Also I did yoga, yes, a lot of it on hands. It's tough to give up workouts when you worked on it for so much. I will have to find something that would not stress my hands. What could it be?

I am also a developer which means I use my thumb a lot at work, which is hard to avoid. That part will be hard to repair.

There is one more factor I'd like to mention:

If you have used in the past a drug from the fluoroquinolone family (Cipro, Levaquin or Avelox)...you need to know that these drugs which are common antibiotics and used for UTIs and pneumonias, can affect the tendons and cause ruptures and other pathology. Somehow they interfere with tendon maintenance. This usually happens AFTER the treatments and is often overlooked by doctors. The toxicity of these drugs is considerable.

This may be a factor for you in addition to extreme physical activity that also stresses tendons.

Tendon injury takes a long time to heal. It might be a good idea to see a hand specialist at this point.

Thanks for information, MrsD,
in fact I did use cipro for UTI, but it was in December 2016, so about 6 months ago. After just few doses my left arm started to shake and give up when i was working out so I found horrible stuff about cipro and requested another antibiotic (which I got).
NOw I am not sure how much damage can 3 or 4 days of cipro can do, and how long effects can last, but after what I read, this medication should not be given to someone who exercises or plans to exercise. Also, you should never ever take NSAIDs (any) during or soon after you are finished with cipro.

Unfortunately the tendon damage I believe goes on for months and even years. These drugs damage DNA...and somehow affect tendon maintenance which may be permanent. I sure hope not.

This effect because of the long delay in onset was first discovered by doctors who used the samples willy nilly on themselves and their families and subsequently later much after the infection was over, ruptured knee tendons and achillies tendons! We had a poster here in the past who ruptured a biceps tendon moving furniture. I have yet to see any research about this explaining how it works, but the fact remains that the tendon damage remains a LONG time after the drug is stopped.

Your age and gender are against you now... lowering estrogen affects many things for women. Also if you have been pregnant in the past, you join women whose tendons change after pregnancy. During pregnancy, the body makes a hormone called relaxin to help the pelvis dilate during delivery. It relaxes ALL tendons and it can weaken some in those with a tendency to have connective tissue problems. Women notice their feet get bigger after pregnancies and this is one obvious sign that relaxin has loosened their feet which are held together by ligaments/tendons. In your case you might have additive triggers for your problems today.

A hand specialist may have a treatment or surgery to help you. At least a hand doctor can give you a support or a brace of some type to immobilize your hand to enable faster healing.

I find that taking corn syrup, corn starch and corn out of my diet reduces myoclonus jerks in my hands. Read labels carefully as things you wouldn’t expect like cough drops and probiotics have corn products in them.
Hope this helps you.
Jean