Miss2000, That's right they don't know. If you had a surgery you could have complications from that job. If you've taken statins, there are issues from that class of drugs. I choose to "turn down" any of their drugs and MAYBE if I could afford and was guaranteed no side effects, I might buy into the Celebrex drug, but that's not the case. So I try things on my own. Plain and simple, doctors only do what they think might help. I'm sure they get plenty frustrated trying to heal their patients. And failing. We need to work on being our own doctors more and more.