[Teancum]

Hello -I am new to the forum.

For the past 1 /12 years I have had severe brain fog and it is getting worse. I have taken every test from my Neurologist, hematologist and Internal Medicine doctors. Recently they discovered that my b6 levels are way out of whack (took three different tests--one per doctor because they could not believe the results)--the last test showed my levels were 245 when the range was 2.1 -21. And I take no supplements or vitamins at all.

Also my alkaline phosphatase levels were very low. Also, my lumbar puncture showed my CSF pressure was 28. And I have extreme pain in my joints (hips, knees and elbows) and muscle pain in my legs. My arms and feet go numb a couple of times an hour for about a minute or two.

My doctors are at a loss. They can not explain the "organic" levels of my b6 or the brain fog or any of the other symptoms.

Any ideas or thoughts would be welcomed. I am getting very frustrated.

Thank you

Teancum

[mrsD]

Welcome to NeuroTalk:

There is a study online on PubMed, about B6 levels found surprisingly high in children with autism, taking no supplements.

I have it on my B6 thread here:
http://neurotalk.psychcentral.com/thread30724.html

Labs vary in the ranges they quote....some go up to 95 or so as normal. Also there is pyridoxine (inactive B6) in many foods today...mostly cereals, bread and pasta.

The test I believe will not separate out activated form P5P from pyridoxine (regular B6). So if you are NOT activating the pyridoxine you eat, it might build up.

Low alkaline phosphotase is better than elevated.
http://www.livestrong.com/article/40...e-phosphatase/
For what it is worth, I've had slightly elevated alkaline phosphotase levels all my life...not extremely high, but just out of range. 30+ yrs of it...nothing bad has happened to me!
No other liver tests are abnormal either.

I wonder if what your B12 levels are as well. Did you have that tested? did your doctor say "normal"? Well you could be low then because lab ranges in US are still reported low as normal.
The new cut off for normal is now 400pg/ml in US. (other countries report it differently). So call them back get your B12 number as well. Did you have Vit D done? You should also have this run and get the numbers for it.

Some tests get done improperly too. So after you get the numerical results, you might consider a retest in 3-6months.
Labs can make mistakes based on how they calibrate their instruments etc.

[Darlene]

Teancum,

It is great to have you come and be with us. You will fine a great number of dear friends to listen when you are in need of ears. Please, just let us know how we can help you out. You will find out we are supportive and relaxing place.

Please keep us up to date on your condition. Again welcome, looking forward to seeing you around. My thoughts and prayers are with you.

[Rrae]

Welcome to NT!

You've found a great place for support and understanding!
Please make yourself right at home and feel free to look through the forums and post anywhere you feel inclined. There's alot of good information here at NT, and lots of caring people.

Just holler if you have any questions or need help finding your way around!
It's great to have you!

Rae