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Parkinson's Disease Clinical Trials For posting and discussion of clinical trials related to Parkinson's Disease, and for the Parkinson Pipeline Project. All are welcome. |
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05-31-2007, 05:56 PM | #1 | |||
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Magnate
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NET-PD LS-1 Creatine in Parkinson’s Disease - Recruiting 1,720 Participants!
Official Study Title: A Multicenter, Double-Blind, Parallel Group, Placebo Controlled Study of Creatine in Subjects with Treated Parkinson’s Disease (PD) Long term Study (LS-1) Sponsor: National Institute of Neurological Disorders and Stroke (NINDS) Study ID: (none) Trial Start Date: 22 Mar 2007 Last Updated Date: 21 May 2007 Summary NET-PD is a large NIH-sponsored effort to find drugs that slow the progression of Parkinson's disease. Recruitment is currently underway for a study of the nutritional supplement creatine in more than 1700 participants. Parkinson's disease (PD) affects nearly a million Americans, a number that will increase over the coming decades as the population ages. Symptoms of PD may include tremor, rigidity or stiffness of the limbs and trunk, slowness of movement, and impaired balance and coordination. These problems occur because as PD worsens, some of the brain cells that control body movement die. This study will determine if creatine—an investigational drug—is able to slow the progression of PD. Creatine, a widely used dietary supplement is thought to improve exercise performance. In animal models and human studies, creatine has been shown to be well-tolerated and may have some ability to protect brain cells. Although basic forms of the supplement are generally available on retail shelves, the creatine used in this study is significantly different. It is a clinical form, called PD-02, and is provided to the study investigators by Avicena Group, Inc. In the NET-PD LS-1 study, 1,720 participants will be randomly assigned to receive either creatine or a placebo (inactive substance). Participation in this study lasts a minimum of 5 years and includes at least 9 follow-up clinic visits and at least 3 telephone calls. Enrollment Expected Enrollment: 1720 Trial Phase Study Phase: Phase 3 (About Phases) Symptoms # Trial does not treat PD symptoms Time Commitment Length of Time Commitment: More than six months Frequency of office visits: At least 9 follow-up clinic visits and at least 3 telephone calls within a minimum of 5 years Inclusion Criteria
Exclusion Criteria
Debbie Fraser & Nita Gardiner Primary Study Coordinators Phone : 585-273-4266 Debbie.Fraser@ctcc.rochester.edu NY USA Local Contacts Lorelei Derwent Study Coordinator University of Calgary Movement Disorders Program Phone : 403-220-8413 Dept. of Clin. Neurosciences Area 3 Neurology, 3350 Hospital DR NW Health Sciences Centre Calgary, AB T2N4N Canada Germaine Mcinnes Study Coordinator University of Alberta Phone : 780-735-8853 10230-111 Avenue Room 0601 Movement Disorders Clinic Glenrose Rehab Hospital Edmonton, AB T5G0B Canada Rebecca Mcmurray Study Coordinator University of Alabama at Birmingham Phone : 205-996-4034 350 Sparks Center 1720 7th Avenue, South Birmingham, AL 35233 USA Lynn L. Marlor Study Coordinator Barrow Neurological Clinics at St. Joseph's Hospital & Medical Center Phone : 602-406-6259 St. Joseph's Hospital & Medical Center 500 West Thomas Road Suite 720 Phoenix, AZ 85013 USA An Hao Tran Study Coordinator Parkinson's & Movement Disorder Institute Phone : 714-378-5074 9940 Talbert Avenue Suite 204 Fountain Valley, CA 92708 USA Connie Kawai Study Coordinator University of Southern California Phone : 323-442-5814 Healthcare Consultation Building II 1520 San Pablo Street, Suite 300 Los Angeles, CA 90033 USA Jessie Roth Study Coordinator University of California, San Francisco Phone : 415-476-9276 Parkinson's Disease Clinic & Research Center 505 Parnassus Ave. M-798 San Francisco, CA 94143 USA Katie Ersted Study Coordinator The Parkinson's Institute Phone : 408-542-5652 1170 Morse Avenue Sunnyvale, CA 94089 USA Tammie Kelsey Study Coordinator Neurodegenerative Disorders Phone : 203-401-4361 60 Temple Street, Suite 8B New Haven, CT 06510 USA Helen Dunn Study Coordinator VA Medical Center Phone : 352-376-1611 1601 Southwest Archer Road Neurology Service (151) Gainesville, FL 32608 USA Kathryn Jemmott Study Coordinator University of Florida Phone : 352-273-5614 McKnight Brain Institute 100 South Newell Drive, Room L3-100 Gainesville, FL 32610 USA Lisa Smith Study Coordinator University of Florida Jacksonville Phone : 904-244-9480 580 West 8th Street Tower 1, 8th Floor Jacksonville, FL 32209 USA Monica Quesada Study Coordinator University of Miami Phone : 305-243-3647 1501 North West 9th Avenue 2nd Fl, Dept. of Neurology D4-5 Miami, FL 33136 USA Holly Delgado Study Coordinator University of South Florida, Movement Disorders Center Phone : 813-844-4453 Movement Disorders Center 4 Columbia Drive, Ste. 410 Tampa, FL 33606 USA Mary Louise Musante Weeks Study Coordinator Emory University Phone : 404-728-4982 Wesley Woods Health Center 1841 Clifton Rd. Room 328 Atlanta, GA 30329 USA Buff Dill Study Coordinator Medical College of Georgia, Movement Disorders Clinic Phone : 706-721-0619 Movement Disorders Clinic 1429 Harper Street HF 1121 Augusta, GA 30912 USA Stephanie Terashita Study Coordinator Pacific Health Research Institute Phone : 808-441-5567 405 North Kuakini Suite 1003 Honolulu, HI 96817 USA Karen Williams Study Coordinator Northwestern University Phone : 312-503-5645 710 No. Lake Shore Dr. Chicago, IL 60611 USA Jeana Jaglin Rush University Medical Center Phone : 312-563-2900 Department of Neurological Sciences 1725 West Harrison Street, Suite 755 Chicago, IL 60612 USA Gina Medalle Study Coordinator Evanston Northwestern Healthcare Phone : 847-657-5875 Department of Neurology 2100 Pfingsten Road, Ste. B110 Glenview, IL 60026 USA Barbara Lokaitis Study Coordinator Southern Illinois University School of Medicine Phone : 217-545-9737 PO Box 19645 Springfield, IL 62794 USA Joann Belden Study Coordinator Indiana University School of Medicine Phone : 317-278-0868 Outpatient Clinical Research Facility 535 Barnhill Drive Room 150 Indianapolis, IN 46202 USA Tamara Gales Study Coordinator University of Kansas Medical Center Phone : 913-588-5250 3599 Rainbow Blvd. Department of Neurology Mail Stop # 2012 Kansas City, KS 66160 USA Renee Wagner Study Coordinator University of Kentucky Clinical Research Phone : 859-323-0028 C201 Kentucky Clinic 740 Limestone Street Lexington, KY 40536 USA Maureen Cook Study Coordinator Ochsner Clinic Foundation Phone : 504-842-2487 1514 Jefferson Highway Dept. of Neurology, 7th Floor New Orleans, LA 70121 USA Colette Hilliard Study Coordinator LSU Health Science Center Shreveport Phone : 318-675-8157 1501 Kings Highway Room 3-436 Shreveport, LA 71130 USA Linda Paul Study Coordinator Beth Israel Deaconess Medical Center Phone : 617-667-9885 330 Brookline Avenue Shapiro 809D Boston, MA 02215 USA Lewis Sudarsky Study Coordinator Brigham & Women's Hospital Phone : 617-732-5405 Neurology Department ASB2 75 Francis Street Boston, MA 02115 USA Becky Dunlop Study Coordinator Johns Hopkins University Phone : 410-955-8795 601 North Caroline Street Suite 5064 Baltimore, MD 21287 USA Kelly Dustin Study Coordinator University of Maryland School of Medicine Phone : 410-328-7809 Department of Neurology 22 South Greene Street, N4W46 Baltimore, MD 21201 USA Kristine Wernette Study Coordinator University of Michigan Phone : 734-936-5894 1500 E. Medical Center Drive B1 H202 Nuclear Medicine Ann Arbor, MI 48109 USA Doozie Snider Study Coordinator Michigan State University Phone : 517-353-8122 Department of Neurology A217 Clinical Center, 138 Service Road East Lansing, MI 48824 USA Susan Peterson Study Coordinator Struthers Parkinson's Center Phone : 952-993-2249 6701 Country Club Drive Golden Valley, MN 55427 USA Patricia Deppen Study Coordinator Washington University School of Medicine Phone : 314-362-8548 660 South Euclid Avenue campus 8111 St. Louis, MO 63110 USA Joanne Field Study Coordinator Duke University Medical Center Phone : 919-668-2842 Duke Health Center at Morreene Road 932 Morreene Road Room 213 Durham, NC 27705 USA Pauline R. Leblanc Study Coordinator Dartmouth Hitchcock Medical Center Phone : 603-650-4165 One Medical Center Drive 2 Buck Road Lebanon, NH 03756 USA Emily Kosa Study Coordinator UMDNJ Robert Wood Johnson Medical School Phone : 732-235-8971 Department of Neurology Suite 6100, 125 Patterson Street New Brunswick, NJ 08901 USA Nita Gardiner Primary Study Coordinator Phone : 585-341-7569 Nita.Gardiner@ctcc.rochester.edu NY USA Elizabeth Hayes Study Coordinator SUNY Downstate Medical Center Phone : 718-270-2945 450 Clarkson Avenue, Dept. of Neurology Box 1213 Brooklyn, NY 11203 USA Barbara Shannon Study Coordinator Northshore-LIJ Health System Phone : 516-562-2905 The Feinstein Institute FPR Medical Research 350 Community Drive Manhasset, NY 11030 USA Stephanie Crocker Study Coordinator OHSU Oregon Health & Science University, Dept. of Neurology Phone : 503-418-1769 Department of Neurology 3181 South West Sam Jackson Park Road Portland, OR 97239 USA Sue Reichwein Study Coordinator University of Pennsylvania, Pennsylvania Hospital Phone : 215-829-7273 Pennsylvania Hospital, Penn Neurological Institute 330 South Ninth Street Philadelphia, PA 19107 USA Stephanie Sendek Study Coordinator Thomas Jefferson University Phone : 215-955-8700 1015 Chestnut Street Suite 520 Philadelphia, PA 19107 USA Gwyn M. Vernon Study Coordinator Thomas Jefferson University/Lankenau Hospital Phone : 610-642-5371 Lankenau Medical Building Suite 161 East, 100 Lancaster Avenue Wynnewood, PA 19096 USA Margaret Lannon Study Coordinator Neurohealth Parkinson's Disease Phone : 401-921-4245 Movement Disorder Center 227 Centerville Rd. Warwick, RI 02886 USA Vicky Salak Study Coordinator Medical University of South Carolina Phone : 843-792-7262 Charleston Memorial Hospital 326 Calhoun Street, Suite 308 Charleston, SC 29401 USA Dorothy Shearon Study Coordinator Vanderbilt University Medical Center Phone : 615-936-0219 2311 Pierce Avenue Room 2217 Nashville, TN 37212 USA Brigid Hayward Study Coordinator University of Texas Southwestern Medical Center at Dallas Phone : 214-648-7976 5323 Harry Hines Boulevard H1-108 Dallas, TX 75390 USA Christine Hunter Study Coordinator Baylor College of Medicine Phone : 713-798-3951 6550 Fannin Suite 1801 Houston, TX 77030 USA Elke Rost-Ruffner Study Coordinator University of Virginia, Department of Neurology Phone : 434-243-5422 Department of Neurology 500 Ray C. Hunt Drive Charlottesville, VA 22903 USA Shannon Lenox Study Coordinator University of Vermont, Dept. of Neurology Phone : 802-656-3876 Department of Neurology, Given Building C-219 89 Beaumont Avenue Burlington, VT 05405 USA Trial Start Date: 22 Mar 2007 Last Updated Date: 21 May 2007 Trial Post date: 18 May 2007 Website Url: http://www.parkinsontrial.ninds.nih.gov/ redline.jpg Full Details: PDTrials.org http://www.pdtrials.org/front/trial_...p?trial_id=161ClinicalTrials.gov http://clinicaltrials.gov/ct/show/NCT00427674?order=1[LIST][*]Complete list of PD trials redline.jpg Parkinson Pipeline Project www.pdpipeline.org Following theapies from pre-clinical development to approval in the Parkinson Pipeline Project Database (see homepage for link to database) redline.jpg
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You're alive. Do something. The directive in life, the moral imperative was so uncomplicated. It could be expressed in single words, not complete sentences. It sounded like this: Look. Listen. Choose. Act. ~~Barbara Hall I long to accomplish a great and noble tasks, but it is my chief duty to accomplish humble tasks as though they were great and noble. The world is moved along, not only by the mighty shoves of its heroes, but also by the aggregate of the tiny pushes of each honest worker. ~~Helen Keller Last edited by Stitcher; 05-31-2007 at 06:45 PM. |
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06-06-2012, 12:01 PM | #2 | ||
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So what happened to this study ? Did it start in 2007 or later ? I saw today that they expect the study to be finished in 2015 !!! That's still a looooong way to go. Anyone involved in this clinical trial ? I guess if the study started in 2007 the results must at least not be too bad because they didn't stop the clinical trial like they did with Coq10 clinical trials ... ?
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