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Parkinson's Disease Clinical Trials For posting and discussion of clinical trials related to Parkinson's Disease, and for the Parkinson Pipeline Project. All are welcome. |
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05-31-2007, 06:28 PM | #1 | |||
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Risk Factors for Progressive Supranuclear Palsy (PSP)
Official Study Title: Genetic and Environmental Risk Factors for PSP Sponsor: National Institute on Aging (NIA) Clinicaltrials.gov ID: NCT00431301 Study ID: 1 R01 AG024040-01A2 Last Updated Date: 14 May 2007 Trial Start Date: 01 Aug 2006 Trial Post date: 23 Apr 2007 Website URL: http://www.clinicaltrials.gov/ct/show/NCT00431301?order=2[B]Summary Summary PSP is a neurologic disorder of unknown origin that gradually destroys cells in specific areas of the brain, leading to serious and permanent problems with the control of gait and balance. The most obvious sign of the disease is an inability to aim the eyes properly, which occurs because of damage in the area of the brain that coordinates eye movements. Persons with PSP also often show alterations of behavior, including apathy as well as progressive frontal disturbances, problems with planning and multitasking. This study will determine: (1) if there is an association between PSP and specific genes of interest; (2) if there is an association between PSP and occupational and/or environmental chemical exposures functionally or structurally similar to known parkinsonian toxicants; and (3) if hypertension or traumatic brain injury prior to symptom-onset is associated with PSP. To disentangle the complex set of factors that contributes to PSP, this study involves 500 PSP cases, 500 age/gender matched primary controls, and 500 secondary controls for genetic confirmation. Understanding the cause of PSP may also help explain the causes of other related diseases such as Alzheimer's or Parkinson’s disease. This multidisciplinary team of movement disorder specialists, epidemiologists, geneticists, biostatisticians, industrial hygienist and toxicologist is well suited to unravel the etiology of PSP. Enrollment Expected Enrollment: 1500 Trial Phase Study Phase: Not Specified (About Phases) Symptoms # Trial does not treat PD symptoms Time Commitment Length of Time Commitment: Less than six months Frequency of office visits: Eligibility Minimum Age: 40 Trial accepts healthy volunteers Inclusion Criteria
Christopher Cunningham, Ph.D. & Whitney Rogers, BA Study Coordinators University of Louisville Phone : 866-777-0448 info@pspstudy.com Louisville, KY 40202 USA Local Contacts Rebecca McMurray Study Coordinator University of Alabama Phone : 205-996-4034 Birmingham, AL 35233 USA Site opening soon University of California at Los Angeles (UCLA) Los Angeles, CA 90095 USA Audrey Strongosky Study Coordinator Mayo Clinic Jacksonville Phone : 904-953-6096 Jacksonville, FL 32224 USA Carol Ingram Study Coordinator Emory College of Medicine Phone : 404-728-6859 Atlanta, GA 30322 USA Maura Deeley Study Coordinator University of Maryland Phone : 410-328-7816 Baltimore, MD 21201 USA David Korosec Study Coordinator Case Western University Phone : 216-844-1880 Cleveland, OH 44106 USA Christine Hunter Study Coordinator Baylor College of Medicine Phone : 713-798-3951 Houston, TX 77030 USA redline.jpg Full Details: PDTrials.org http://www.pdtrials.org/front/trial_...p?trial_id=161ClinicalTrials.gov http://clinicaltrials.gov/ct/show/NCT00427674?order=1[LIST][*]Complete list of PD trials redline.jpg Parkinson Pipeline Project www.pdpipeline.org Following theapies from pre-clinical development to approval in the Parkinson Pipeline Project Database (see homepage for link to database) redline.jpg
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You're alive. Do something. The directive in life, the moral imperative was so uncomplicated. It could be expressed in single words, not complete sentences. It sounded like this: Look. Listen. Choose. Act. ~~Barbara Hall I long to accomplish a great and noble tasks, but it is my chief duty to accomplish humble tasks as though they were great and noble. The world is moved along, not only by the mighty shoves of its heroes, but also by the aggregate of the tiny pushes of each honest worker. ~~Helen Keller Last edited by Stitcher; 05-31-2007 at 06:44 PM. |
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