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New Clinical Trials

A Study of Botox in the Management of Uncontrollable Movements in PD - "The primary objective of this study is to determine whether intramuscular injections of Botox in selected cervical (neck) muscles can reduce levodopa-induced peak-dose dyskinesias (LID), or uncontrollable movements, in the cervical region in adult participants with idiopathic PD."Learn more


Effects of Coenzyme Q10 in Progressive Supranuclear Palsy (PSP) - "The clinical syndrome of PSP responds poorly to all available forms of therapy used in PD. Currently, no effective treatment exists. Coenzyme Q10 in high doses has been shown to be a beneficial therapy in PD and might possibly be a beneficial therapy for PSP. This study will compare the efficacy, safety and tolerability of Coenzyme Q10 versus placebo in participants with atypical parkinsonian syndrome PSP."Learn more

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Tell Us Your Story

"At times, we receive correspondence from people living with Parkinson's about their clinical trial experience. We thought we'd share some of these stories with you, like the one below from Linda, who was diagnosed with PD two years ago and has since been involved with three clinical studies.

"If you have participated in a trial that you found through PDtrials we'd love to hear from you. Sharing your experience provides us with insight that only you can offer and helps ensure that PDtrials.org is a valuable resource to the PD community."

Please email us at info@pdtrials.org to tell your story.


My Experience in Parkinson's Clinical Trials

"I was diagnosed with PD in October of 2005 at the age of 50. My left-sided tremors remain relatively mild. Because they are mild my neurologist said "See you in a year!" I immediately started "googling" everything as I could not imagine sitting around for a year waiting for my symptoms to worsen. I felt so powerless."
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Gene Mutation Linked to Parkinson's Disease

"People who carry a certain gene mutation appear to have a greater risk for getting PDand for getting it at a relatively early age, new research suggests. The study authors also found that because Ashkenazi Jews -- those with an Eastern European background-- are more likely to carry this gene mutation, this population may run an even higher risk for the disease. An estimated 90 percent of American Jews are of Ashkenazi lineage. Study lead author Lorraine N. Clark, a researcher at Columbia University, described her team's findings as "unique and different."
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Rewiring the Brain: TIME Magazine Looks at Deep Brain Stimulation

"It's harder than you think to say hello to your mother--at least in terms of the work your brain has to do. A glimpse of Mom must first register on your occipital lobes as a pattern of light and shadow. From there it is relayed to your memory center, where it is identified by comparison with every other face you've ever seen. You must then summon the speech centers in your frontal lobes, which recruit your breath and muscles and at last allow you to utter the words Hi, Mom. The fact that recognizing and acknowledging a familiar person is such a complex thing made it all the more remarkable in early August when scientists announced that a 38-year-old man had managed to pull it off. The man...had suffered severe brain damage in a 1999 mugging and spent the past eight years in the dark cognitive well that neuroscientists call a minimally conscious state. Improbably, however, he can now greet both his parents. He can identify objects, hold very brief conversations and watch movies, and he recently recited the first 16 words of the Pledge of Allegiance...None of this is the stuff of functioning adulthood, but all of it is huge for a person who was never supposed to manage anything like it again. And all of it is a result of the growing therapeutic science of deep-brain stimulation (DBS)."
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Parkinson's Disease Dementia is Studied

"U.S. medical scientists have discovered an intermediate stage in patients with PD that might be predictive of eventual dementia. Researchers from the Mayo Clinic, Sun Health Research Institute and the Arizona Parkinson's Disease Consortium studied how patients with PD transition to an immediate state of cognitive problems before developing dementia. Dementia is associated with Parkinson's in up to 40 percent of patients."
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CISCRP hosts AWARE for All Workshops to Advance Clinical Research Education in Indianapolis on November 3rd

"The Center for Information and Study on Clinical Research Participation (CISCRP) will host Indianapolis' 2007 Annual Workshops to Advance Clinical Research Education on November 3rd. Educational programs include informational workshops with top doctors and researchers, thank you receptions for local clinical research participants, health screenings, and additional resources. AWARE for All workshops are held several times a year in metropolitan areas around the U.S. and are free and open to the public."
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Current Trial News
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