Parkinson's Disease Tulip


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Old 12-28-2009, 12:02 AM #1
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Default A little Perrier, maybe a lot more dopamine?

Okay, so here I am not able to sleep thanks to dopa agonist and up reviewing some treatments from the PD Pipeline database...I ran across this wonderfully odd site. Not quite sure what to make of this; I think the idea of this Open Access scientific research site is fantastic for curious, outspoken folks like us but wonder how legit or authoritative this may be (or not be) to the rest of the PD research 'machine':

Hydrogen in Drinking Water Reduces Dopaminergic Neuronal Loss in the
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Mouse Model of Parkinson's Disease


Citation: Fujita K, Seike T, Yutsudo N, Ohno M, Yamada H, et al. (2009)
PLOS (Public Library of Science)

"Antioxidants not only in foods but also in drinking water would offer a great advantage over other forms of antioxidant therapy. In fact, it was reported that drinking electrolyzed H2-saturated water showed an effect in reduction of oxidative stress in rats, as measured by urine oxidized guanine and hepatic lipid peroxide [14]. Recently it was also shown that drinking H2-saturated water, instead of inhaling H2 gas, prevents cognitive impairment by reducing oxidative stress [3]. According to Nagata et al. [3], even in drinking water, H2 can be delivered to the blood in minutes.

Using the widely accepted PD model, we have tested the effect of H2-containing drinking water on the MPTP-induced loss of dopaminergic neurons. Here we show that drinking H2 water may potentially offer a great advantage over other forms of antioxidant therapy, particularly for chronic pathological conditions such as PD."

Okay, so drinking our water with gas helps maintain whatever dopamine cells we have left- okay easy enough to add to the DM cough syrup regimen, but is this for real?

Apparently, this site is open access and reflects the philosophy of its parent organization "The Public Library of Science". Researchers submit results of original research and undergo a peer editing review; readers are encouraged to comment. Seems legit, search Parkinson's and see all the work that pops up- finally, a source that actually shares full access to us lowly patients!

What do you all think?

Laura
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Old 12-28-2009, 12:14 AM #2
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Does Perrier really have hydrogen in it ? I know it has gases other than co2 but thought it was nitrogen.
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Old 12-28-2009, 12:45 AM #3
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Default It did have benzene...

Quote:
Originally Posted by suzi View Post
Does Perrier really have hydrogen in it ? I know it has gases other than co2 but thought it was nitrogen.
Sorry, my mistake. I didn't mean to misinform- Perrier does indeed have nitrogen, not hydrogen.

I am mixing it up with the trend toward marketing anti-oxidant waters like Penta.

In the meanwhile, I ran across this site that debunks hydrogenated or any other claim to anti-oxidant rich water:

Wonky Water Weirdness and Quackery


Hmmm...
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Old 12-28-2009, 09:07 AM #4
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Maybe it's the bubbles - like the champagne thing?
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Old 01-01-2010, 09:41 PM #5
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Default research?

When analyzing research, one needs to keep in mind lots of questions. Things like who were the subjects (mice, in this case), how many were tested, did they use testing methods that really tested what they were looking at, how did they analyze their results, and how far can one realistically strech the results and a few questions to keep in mind when reading. How much of this water would a great big human have to drink to compare with what the mice were fed? How close is a mouse's brain and body to a humans? I like reading research, so the site you found sounds like fun! But interpret with caution!

Last edited by Mouse; 01-01-2010 at 09:43 PM. Reason: The icon implys approval - didn't mean that
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Old 01-04-2010, 11:16 PM #6
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Hi, the article is here. I don't have time to read it:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2747267/
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