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01-18-2010, 08:35 AM | #1 | |||
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In Remembrance
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This is a novel way of investigating a defective Blood-Brain Barrier, (BBB).
http://www.google.com/url?sa=X&q=htt...Jz6H5Dhs3D8pKA Tim Mhyre says: "Brains are mysterious things. Hidden behind the protective skull and blood-brain barrier," .... there is no way to effectively diagnose many of the disorders that cripple it – much less predict their development." However, if the BBB is defective, analysis of the blood that flows through the brain can give new information "So he asks – why can’t it tell us about Alzheimer’s and Parkinson’s disease, diagnosed in about six million Americans, as well as traumatic brain injury (TBI)," "....these diseases promote a breakdown in the blood-brain barrier that normally restricts passage of biological materials in to and out of the brain. So these substances leak into the blood, Mhyre says, and can be collected through a simple blood draw in the arm." I think it is not the PD that causes the defective BBB, but the defective BBB causes the disease. However, it is a novel idea to measure what comes OUT of the brain and into the blood that does not normally leak out in a healthy person. As he says, it could be a surefire way of diagnosing PD. Then you could follow progression of the disease by a simple blood test, and also evaluate treatments, by following what gets into the bloodstream which normally should not be there. Ron
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Diagnosed Nov 1991. Born 1936 |
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"Thanks for this!" says: | Conductor71 (01-20-2010), RLSmi (01-18-2010) |
01-18-2010, 01:11 PM | #2 | |||
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If I remember correctly, the Australians have been working on developing a blood test to diagnose PD for a few years now. You may want to do a web search to see what you can find.
http://psychcentral.com/news/2007/04...nsons/784.html http://www.sciencedaily.com/releases...0426093416.htm GregD
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"You can't fight City Hall, but you can pee on the steps and run." --Gary North Last edited by GregD; 01-18-2010 at 01:16 PM. Reason: to add links |
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01-19-2010, 09:48 PM | #3 | ||
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Thanks Ron and Greg!
Blood test for PD would be great. I often wondered if detecting alpha-synuclien or similar protein in the blood could be developed as a screening tool for PD. For some strange reason, I just assumed that it was tried and tested. Good to know some one is developing a test. Laura, Just remembered your Biomarker post; this could be a serious biomarker for PD. Girija |
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"Thanks for this!" says: | Aunt Bean (01-28-2010) |
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