I am very intrigued by your MDS saying he can see brain changes on the mri from the mirapex-if you can find out what changes he sees by asking him, please let us all know! I would be curious as to how the MDS can tell the brain changes he sees are attributable to the mirapex as opposed to PD progression or something else.

We have tried stopping mirapex several times and the pain is unbearable, even trying to reduce the amount we took was a mistake and we had to go back. We would love to get off of it, because of the brain fog, sleepiness, and other side effects, but just cannot seem to do it. Let us know how it goes for you, and if there is anything you do during the weaning off phase that helped get you through it. Thanks!