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02-12-2010, 11:38 PM
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Blood Brain Barrier
New blood brain barrier study findings have been reported from ArmaGen Technologies, Inc. Today's Medical & Research News, February 12th, 2010 http://www.newsrx.com/health-articles/1758909.html A new study, 'Comparison of blood-brain barrier transport of glial-derived neurotrophic factor (GDNF) and an IgG-GDNF fusion protein in the rhesus monkey,' is now available. "The brain drug development of glial-derived neurotrophic factor (GDNF) is prevented by the lack of transport of this protein across the blood-brain barrier (BBB). GDNF transport across the BBB can be made possible by re-engineering the neurotrophin as a fusion protein with a genetically engineered monoclonal antibody (MAb) against the human insulin receptor (HIR), which crosses the BBB on the endogenous insulin receptor," scientists in the United States report.
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New blood brain barrier study findings
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