In fact, I don't usually drink green tea. I take one capsule of this:
http://www.super-smart.eu/en--Green-...utrients--0520
every morning together with Azilect.

Saw this thread and joined the forum just to discuss.

I agree that ECGC can be synergistic and is important. The first article below should be available by googling and says the same thing in an in vitro model.

But as pointed out - the key is to kind the correct dosing. I don't know if you can extrapolate dosing in mice to humans. For example, dosing of rasagiline in mice for its affect on MSA was done at 2.5mg/kg (see study below). However, most people take .5 mg or 1 mg. That is obviously minuscule compared to the mouse concentration. I'd love to find someone who can help us determine the correct dosage.

There are very few human studies with non-pharmaceuticals - very disappointing. There is low cost and money available for in vitro and mice studies but just nothing when it comes to humans.

The other flavanoid that is worth considering is Baicalein/Chinese Skullcap - it disaggregates alpha-synuclien and is iron chealting as well. Again though some studies referenced below suggest more is not better.

Rifampin is also now being studied as well - but that is an antibiotic.

Finally, I can't speak to that specific supplement referenced above but Jarrow makes a good ECGC product and they are GMP certified (high manufacturing credentials).

Cheers!

Effects of Various Flavonoids on the α-Synuclein Fibrillation Process; Parkinson's Disease
Volume 2010 (2010), Article ID 650794, 16 pages; doi:10.4061/2010/650794

Rasagiline is neuroprotective in a transgenic model of multiple system atrophy. Exp Neurol. 2008 Apr;210(2):421-7. Epub 2007 Dec 4.

The effects of the cyclosporin A, a P-glycoprotein inhibitor, on the pharmacokinetics of baicalein in the rat: a microdialysis study; Br J Pharmacol. 2002 December; 137(8): 1314–1320. Published online 2002 November 27. doi: 10.1038/sj.bjp.0704959
Treatment at 10, 30 or 60 mg/kg i.v. - suggests only 30 and 60 mg/kg were detectable in rat brain

Baicalein attenuates methamphetamine-induced loss of dopamine transporter in mouse striatum; Toxicology; 2006 Sep 21;226(2-3):238-45. Epub 2006 Jul 1.
Suggests pretreatment .3 - 1mg/kg i.p. (negative impact at 3mg/kg and over)

Baicalein exerts neuroprotective effects in 6-hydroxydopamine-induced experimental parkinsonism in vivo and in vitro; Pharmacol Biochem Behav. 2009 Jun;92(4):642-8. Epub 2009 Mar 25.

Rifampicin inhibits alpha-synuclein fibrillation and disaggregates fibrils; Chem Biol. 2004 Nov;11(11):1513-21.

Rifampicin reduces alpha-synuclein in a transgenic mouse model of multiple system atrophy.
Neuroreport 2008;19(13):1271-6.

Iron-binding and anti-Fenton properties of baicalein and baicalin; J Inorg Biochem. 2009 March; 103(3): 326–332. doi: 10.1016/j.jinorgbio.2008.11.003

FYI for the ladies: if anyone has interstitial cystitis, green tea, and esp. green tea extract will provoke a major episode...