From the NIH and less than a year old. Download the PDF, but bookmark the online version. The links down the right hand side will take you as far as you want to go. And if you want it short and sweet, just go to Table #1. A good use of the tax dollar.

http://www.ncbi.nlm.nih.gov/pmc/arti...7/?tool=pubmed

Rick,

I think you mentioned before that you were going to try adding EGCG into daily rotation. Have you run across any authoritative source for dosage recommendations for a dopamine starved brain? Most everything involves a cocktail of supplements and EGCG at a fairly low dose. Have you seen anything countering a low dose as more or less beneficial in PD?

Thanks,

Laura

Not exactly what you asked for. Sort of like life.

Safety of green tea
Green tea, as a popularly consumed beverage, is relatively non-toxic [66]. Phase I trial in 17 patients with advanced lung cancer showed that the maximum tolerated dose of green tea extract was 3 g/m2 per day [59]. No severe adverse effects have been reported in association with the medicinal use of green tea [67]. Consumption of high doses of green tea or green tea extract (i.e. 5–6 litters per day) may cause nausea, vomiting, abdominal bloating/pain, dyspepsia, flatulence and diarrhea [59,67]. Excessive consumption of caffeine from green tea may also cause central nervous system stimulation such as dizziness, insomnia, tremors, restlessness, confusion, diuresis (i.e. increasing urine output), heart rate irregularities and psychomotor agitation [67].
Human studies did not show severe adverse effects among volunteers who took 15 tablets of green tea per day (i.e. 2.25 g green tea extracts, 337.5 mg EGCG and 135 mg caffeine) for 6 months [68,69]. A randomized, placebo-controlled trial (n = 40) found no adverse effect in healthy individuals who took green tea polyphenols in the amount equivalent to the EGCG content in 8–16 cups of green tea once a day or twice a day in divided doses for four weeks [69].
From http://www.ncbi.nlm.nih.gov/pmc/arti...6/?tool=pubmed

Also, the paper combining green tea extract and rasagaline used "sub-clinical" doses of both and achieved a synergistic amplification that presumably would have been lost at higher doses. It just keeps coming up with these complex plants that a little bit helps but a little more does not.

I wonder if one might combine the most promising half-dozen in a big old pepper mill on the dinner table and have a constant but low level exposure?

What I've read indicates that at the higher doses, green tea extracts are used to fight cancer...at the low doses, they help us. Too much is NOT a good thing for a PWP, unless he/she is also dealing with cancer, and then I don't know what in the world you would do.

I had a previous post about this linking Dr. Mandel's video where she basically says just this. Personally, we drink green tea, as I feel there are a lot of other "things" in it that might help. If I take just the ECGC, I might be able to get a lot more of it in me...but I lose the other bioflavanoids, which I want. It's like mucuna, we all suspect there's a whole lot more in there than just the dopamine, including a natural form of carbidopa, and who knows what all else, but it seems to work pretty well all together.