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05-12-2010, 06:59 AM
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Pramipexole Successfully Treats Depressive and Motor Symptoms
Medscape May 11, 2010 — The dopamine agonist pramipexole improves depressive symptoms in patients with Parkinson's disease (PD), according to results of a new ... Cells Prevented From Destroying Defective Mitochondria By Mutations That Cause Parkinson's Disease Medical News Today Tue, 11 May 2010 08:34 AM PDT Mutations that cause Parkinson's disease prevent cells from destroying defective mitochondria, according to a study published online May 10 in the Journal of Cell Biology. Defects in the ubiquitin ligase Parkin are linked to early-onset cases of this neurodegenerative disorder. The wild-type protein promotes the removal of impaired mitochondria by a specialized version of the autophagy pathway ...
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