BBB dysfunction
 

Rick, you are right, I can't leave you all for 5 minutes without you hi-jacking my thrread LOL
(before Ron gets back and finds that his BBB thread was thoroughly hijacked in his absence.)
However, back to BBB again.
The ref below says
"...caffeine helps stabilize the blood-brain barrier, an assembly of cells that keeps molecules in the blood from entering brain tissues."
"... caffeine maintained the “immune privilege” of the brain by recovering the functioning of this barrier and its ability to protect the brain from harmful levels of chemicals.".

http://detikinfo.blogspot.com/2010/0...cognitive.html

More and more, I find that repair of a damaged BBB takes a long time. This ref says the repair by caffeine takes long term.
This fits in with curcumin which also repairs the BBB. I have warned people who go on to curcumin, that they should not expect an instant miracle. It takes possibly a year or more to show an improvement.
Ron