Quote:
Originally Posted by girija
When i was on Mirapex, my sleep patterns or lack there of were very similar to what you mentioned. I could go without sleep for a couple days. I just got off Mirapex and switched to Requip XL. I see a major change in my sleep patterns. It is so wonderful to feel sleepy and actually sleep for 5-6hrs every night. Mirapex-induced insomnia and other compulsive behaviors are almost gone within a month of switching to Requip. However, does anyone know what Requip XL is capable of doing????
Girija
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Girija,
We have had similar experiences with the agonists. I switched to Requip, then Requip XL and love that I do now actually experience hunger pains and sleepiness at night- the once a day formulation makes a world of difference for me. You end up with less of a dopamine rush based on the med half lives. I do believe there is now a Mirapex once daily as well - it was approved by the FDA in February 2010. However, all the guides explicitly state that it is intended for early, not advanced, PD! Does anyone know why this is? If we look at Requip XL it indicates patients at all stages may benefit.
I found this direct guide which has comprehensive info on
Requip XL. I am cautious, like Giriija, it seems to good to be true, so I am always waiting for the proverbial other shoe to drop.
A word of caution on adding an anti-depressant to the mix. I added Cymbalta ER (one a day) and found that I am now awake the entire night...not exactly what I wanted. Sigh.
Laura
05-28-2010, 07:16 PM
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