Parkinson's Disease Tulip


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Old 02-04-2007, 07:27 AM #1
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Default bacterial toxins

A very good reason to take green tea extracts. Note that just one systemic exposure was still rolling a year later. H pylori, gum disease, house dust, gut microflora, etc. - all are sources. And if it crosses your path while you are still in the womb, you are hyper-responsive to it. But the ingredients in green tea seem to stop it in its tracks.
-Rick


1: Glia. 2007 Apr 1;55(5):453-62.

Systemic LPS causes chronic neuroinflammation and progressive neurodegeneration.

Qin L, Wu X, Block ML, Liu Y, Breese GR, Hong JS, Knapp DJ, Crews FT.

Bowles Center for Alcohol Studies, School of Medicine, University of North
Carolina at Chapel Hill, Chapel Hill, North Carolina.

Inflammation is implicated in the progressive nature of neurodegenerative
diseases, such as Parkinson's disease, but the mechanisms are poorly understood.
A single systemic lipopolysaccharide (LPS, 5 mg/kg, i.p.) or tumor necrosis
factor alpha (TNFalpha, 0.25 mg/kg, i.p.) injection was administered in adult
wild-type mice and in mice lacking TNFalpha receptors (TNF R1/R2(-/-)) to
discern the mechanisms of inflammation transfer from the periphery to the brain
and the neurodegenerative consequences. Systemic LPS administration resulted in
rapid brain TNFalpha increase that remained elevated for 10 months, while
peripheral TNFalpha (serum and liver) had subsided by 9 h (serum) and 1 week
(liver). Systemic TNFalpha and LPS administration activated microglia and
increased expression of brain pro-inflammatory factors (i.e., TNFalpha, MCP-1,
IL-1beta, and NF-kappaB p65) in wild-type mice, but not in TNF R1/R2(-/-) mice.
Further, LPS reduced the number of tyrosine hydroxylase-immunoreactive neurons
in the substantia nigra (SN) by 23% at 7-months post-treatment, which progressed
to 47% at 10 months. Together, these data demonstrate that through TNFalpha,
peripheral inflammation in adult animals can: (1) activate brain microglia to
produce chronically elevated pro-inflammatory factors; (2) induce delayed and
progressive loss of DA neurons in the SN. These findings provide valuable
insight into the potential pathogenesis and self-propelling nature of
Parkinson's disease. (c) 2007 Wiley-Liss, Inc.

PMID: 17203472 [PubMed - in process]
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Born in 1953, 1st symptoms and misdiagnosed as essential tremor in 1992. Dx with PD in 2000.
Currently (2011) taking 200/50 Sinemet CR 8 times a day + 10/100 Sinemet 3 times a day. Functional 90% of waking day but fragile. Failure at exercise but still trying. Constantly experimenting. Beta blocker and ACE inhibitor at present. Currently (01/2013) taking ldopa/carbadopa 200/50 CR six times a day + 10/100 form 3 times daily. Functional 90% of day. Update 04/2013: L/C 200/50 8x; Beta Blocker; ACE Inhib; Ginger; Turmeric; Creatine; Magnesium; Potassium. Doing well.

Last edited by reverett123; 02-04-2007 at 07:31 AM. Reason: pre-coffee illiteracy
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Old 02-04-2007, 12:54 PM #2
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Default

I also have a bacterial infection from my teeth falling apart recently and have thought of little else over the last couple of days. I have an appointment on Tuesday and am going to seriously question the possibility of getting dentures.

This isn't the first infection I've had and 3 root canals and crowns aren't going to solve the problems permanently.

The oddest thing tho, is that my face and jaw actually feel relaxed without the crown.

Medications are ruining some of our teeth. Never thought of myself with dentures, but it seems the most convenient and hygenic way to deal with early onset teeth crumbling.

Modern chemistry - can't live with it, can't live without it.

paula
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Old 02-06-2007, 07:52 PM #3
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Frown bacterial infections...

You`ve really got me thinking now...about infections.
You know something,I`ve had that many illnesses that I sort of take it in my stride,and I guess have been quite flippant about my health history.
Yet...now you`ve come to mention it...I wonder how much of the initial infection lingers after supposed treatment and thus weakening the system.

My medical history is way too bad looking back.I must be absolutely loaded with toxins as most of my life has been filled with antibiotics which I know can deplete the good bacteria.
My immune system must be well and truly shot.

My medical history...for what it`s worth;
7 yrs old ...tonsils out because of continual throat infections. Following this op I had chronic ear-ache [important for later]
11 yrs old ....septic arthritis in left hip [was told the germ could have lay
dormant for years and may have arisen through an open wound.]
mid to late teens...gromits in right ear...discovered I was deaf
late teens... another op to replace them.
21 yrs...some sort of grafting in my right ear to help correct deafness.
mid 20`s ....severe mastoid trouble....big op...and could have died from the severity of the infection
early 30`s...back in hospital after birth of first child..pelvic infection.
various tooth abscesses
pleurisy three times in a year,and then again some time later.

and intermittant with these landmarks, are minor ear infections,chest infections and tooth abscesses etc etc.

What I am getting at is...for all these infections,I have invariably been dosed with antibiotics which must have depleted my immune system do you think?

So.,..if this BIGGY,...the pylori thing happened along...he would be quids in do you reckon.I would be an easy target...no?

BEMM? This is where I steal your expletive when I look back over my medical past.

BUMMER!!!!!

Reveretti...what do you make of this?
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Old 02-06-2007, 10:49 PM #4
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My doctor does not recommend green tea for me because of the high caffeine content. Before I knew that, I drank it religiously because of Posts by reverett123 on the old forum. Parkinson's disease weakens our immune system, leaving us more open to all bacteria and viruses by leaving a weakened defense system. During stressful times it gets worse.

Please be careful when recommending a particular food or drug based on a study on this site. Dumb people like me, may not do any research or talk it over with their doctor and end up hurting themselves.

Vicky
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Old 02-07-2007, 01:09 AM #5
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Default an interesting point Vicky...

...but did he tell you that according to medical research,70-80 percent of the caffeine consumed is not actually absorbed by the body.I guess it all depends on how much you consume on a daily basis...down to common sense .
However,according to my research...green tea has similar caffeine content as a cup of black tea,but still not nearly as much as coffee or coca cola.It still remains the "tea" that retains the highest content of phytonutrients so this may offset the "downside" of the caffeine.

Again,there are bound to be exceptions of which you Vicky ,are one.Fruit is meant to be good for you,and indeed [in the uk] is marketed with the slogan that we should consume 5 pieces of fruit a day.
Well firstly I know someone who cannot eat citrus fruits because of a sensitive gut...but we are back to common sense and balancing what is good for ourselves individually.

My motto is "If it works for you...then go for it"...so if I jhad my way,everyone would be prescribed half a pint of draught guiness a day.
It works for me....
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