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08-31-2010, 02:28 PM
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Magnate
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http://www.globes.co.il/serveen/glob...85348&fid=1725
http://www.intecpharma.com/levodopa-...s-disease.html "Both of these phenomena are believed to be a result of the pulsatile stimulation of striatal dopamine receptors, caused by fluctuations in Levodopa blood concentrations between doses. To date, a satisfactory sustained-release formulation of Levodopa has not been possible because LD is absorbed mainly in the upper intestines and a slow release product that has passed the area of absorption is not effective. " -------- does that explain why CR is so unpredictable, at least for me? |
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