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10-09-2010, 08:58 AM | #11 | |||
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In Remembrance
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My money is betting that they are talking about Exendine-4 that Tom Isaacs is flogging gila monsters to produce. I found a corporate presentation for investors from early this year at pharmain.com/pdfs/Non-ConfidentialTechnologyPresentation.pdf
Download and look at the last three or four pages. Among other interesting tid bits are "PGC protects GLP-1 from DPP-IV degradation". That is exactly what Tom and crew are into. GLP-1 is the peptide that rebuilds the brain and DPP-IV is the enzyme that prevents it from working.
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Born in 1953, 1st symptoms and misdiagnosed as essential tremor in 1992. Dx with PD in 2000. Currently (2011) taking 200/50 Sinemet CR 8 times a day + 10/100 Sinemet 3 times a day. Functional 90% of waking day but fragile. Failure at exercise but still trying. Constantly experimenting. Beta blocker and ACE inhibitor at present. Currently (01/2013) taking ldopa/carbadopa 200/50 CR six times a day + 10/100 form 3 times daily. Functional 90% of day. Update 04/2013: L/C 200/50 8x; Beta Blocker; ACE Inhib; Ginger; Turmeric; Creatine; Magnesium; Potassium. Doing well. |
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10-09-2010, 09:23 AM | #12 | ||
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Senior Member
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10-09-2010, 09:42 AM | #13 | ||
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In Remembrance
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From Katie Hood in part: "I know we've led a lot of work on pioglitazone in PD. what's exciting is that we just launched/are launching a new "repurposing" RFA - meant to specifically fund work to show that drugs developed for other diseases might help PD. $3M i believe. so work like this has a way to get funded!"
From Todd Sherer: "Just for more information, based on work supported by the MJFF, the NIH has awarded funding for a clinical trial on pioglitazone that is scheduled to start early next year." Thanks to you both for responding!
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paula "Time is not neutral for those who have pd or for those who will get it." |
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"Thanks for this!" says: | Conductor71 (10-09-2010) |
10-09-2010, 01:35 PM | #14 | ||
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Thanks for that, Paula.
The ongoing exendin trial in the UK may provide some answers as well. Is anyone here participating in that trial or knows someone who is? Quote:
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10-09-2010, 08:57 PM | #15 | |||
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Senior Member
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Exendin-4 as a Treatment for Parkinson's |
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10-10-2010, 01:07 PM | #16 | ||
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10-10-2010, 04:57 PM | #17 | |||
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In Remembrance
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Tom and the Trust are miniature versions of MJFF and raise funds for multiple studies.
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Born in 1953, 1st symptoms and misdiagnosed as essential tremor in 1992. Dx with PD in 2000. Currently (2011) taking 200/50 Sinemet CR 8 times a day + 10/100 Sinemet 3 times a day. Functional 90% of waking day but fragile. Failure at exercise but still trying. Constantly experimenting. Beta blocker and ACE inhibitor at present. Currently (01/2013) taking ldopa/carbadopa 200/50 CR six times a day + 10/100 form 3 times daily. Functional 90% of day. Update 04/2013: L/C 200/50 8x; Beta Blocker; ACE Inhib; Ginger; Turmeric; Creatine; Magnesium; Potassium. Doing well. |
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10-10-2010, 10:23 PM | #18 | ||
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In Remembrance
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Quote:
paula
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paula "Time is not neutral for those who have pd or for those who will get it." |
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10-11-2010, 04:00 PM | #19 | ||
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Junior Member
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Sorry all. Been ill since wpc and trying to catch up.
For the record neither I nor anyone else at CPT has ever said Cogane will be the "cure" for Parkinson's. We continue to be excited about the product and our support of it assisted the pharma company which owns it in securing funding to the tune of £25million. Without our support the product might never have made it to clinical trial - so feel rather disgruntled about negative comments, but perhaps I misread them and no matter anyway. Just wanted to get that straight. No need for further comment. Exendin - yes - it's looking more and more exciting particularly in view of articles which I am forwarding to Rick as I don't know how to attach them here. PIlot study has started a Queen Square in LOndon. Will keep you posted. Tom |
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"Thanks for this!" says: | caldeerster (10-11-2010), Conductor71 (10-11-2010), jeanb (10-11-2010), just_me_77 (10-14-2010), lindylanka (10-12-2010), reverett123 (10-11-2010), soccertese (10-12-2010) |
10-12-2010, 07:15 AM | #20 | ||
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In Remembrance
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It's no wonder you came down with something. What a job it must have been to pull that off! We enjoyed it and see you have a very nice group working with you. It was a wonderful place to hang out but i thihk each wii machine has their own 'slant' as my bowling was terrible and i'm pretty decent at home.
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paula "Time is not neutral for those who have pd or for those who will get it." |
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