Parkinson's Disease Tulip


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Old 10-20-2010, 11:07 PM #4
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Default Definitely a hormonal connection

Quote:
Originally Posted by Peony View Post
I've been taking amlodipine because it was the best cc blocker I could obtain from Kaiser, thinking (hoping) it was similar enough to isradipine. Turns out apparently not. The other thing I did soon after diagnosis was to slap on a low-dose bio-identical estrogen patch, since I've read several times about an estrogen-PD connection. Just one example: women who get full hysterectomies (including ovaries) before age 50 have a higher risk of PD, and risk increases the younger the age at removal.
There is definitely a hormonal connection. I had a baby shortly after my diagnosis and the pregnancy definitely had a permanent, negative impact on the PD. I have talked to several young onset women who experienced the same; one of whom had no motor symptoms emerge until after she had been breastfeeding for a few months.

Researchers are just now starting to explore how PD is different for women, and we just posted an article abstract in another thread that suggests sex hormones may be treatment approaches down the road. Progesterone is thought to play a key role as well in neurodegenerative disease as well.

Laura
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