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Old 11-29-2010, 09:50 AM #71
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Lightbulb more vitamin D

Thanks soccertese and others for your great personal experimentation and information about vitamin D. The following from the above referenced article was eye-opening to me,


"Reported biological effects in the nervous system include the biosynthesis of
neurotrophic factors and at least one enzyme involved in neurotransmitter synthesis[72]. Vit-D3
metabolites can also inhibit the synthesis of inducible nitric oxide synthase (iNOS) and increase
glutathione levels, suggesting a role for the hormone in brain detoxification pathways. Vit-D is involved
in the glutathione cycle and in cysteine transport. Brain gamma-glutamyl transpeptidase (gamma-GT) is
increased after vit-D administration and this positive effect was noted in pericytes and parenchymal
astrocytes. Gamma-GT is thought to participate in the scavenging of reactive oxygen species and it was
hypothesized that vit-D could be an effector controlling detoxification processes in the brain[73]."


Besides the detoxification- also affecting the glutathione cycle and the synthesis of neurotropic factors!
Sounds promising to me.
Thanks, I'm going to make a point of more sun exposure.


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Old 11-30-2010, 12:45 AM #72
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Quote:
Originally Posted by VICTORIALOU View Post
Thanks soccertese and others for your great personal experimentation and information about vitamin D. The following from the above referenced article was eye-opening to me,


"Reported biological effects in the nervous system include the biosynthesis of
neurotrophic factors and at least one enzyme involved in neurotransmitter synthesis[72]. Vit-D3
metabolites can also inhibit the synthesis of inducible nitric oxide synthase (iNOS) and increase
glutathione levels, suggesting a role for the hormone in brain detoxification pathways. Vit-D is involved
in the glutathione cycle and in cysteine transport. Brain gamma-glutamyl transpeptidase (gamma-GT) is
increased after vit-D administration and this positive effect was noted in pericytes and parenchymal
astrocytes. Gamma-GT is thought to participate in the scavenging of reactive oxygen species and it was
hypothesized that vit-D could be an effector controlling detoxification processes in the brain[73]."


Besides the detoxification- also affecting the glutathione cycle and the synthesis of neurotropic factors!
Sounds promising to me.
Thanks, I'm going to make a point of more sun exposure.
thank rick, it's his thread.
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Old 11-30-2010, 12:46 AM #73
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Quote:
Originally Posted by Conductor71 View Post
Just as a side note on the importance of sunlight. I don't know about all of you, but as a kid I was outside a lot, year round...yes even in the dead of a bleak, dreary Michigan winter, I ice skated on a lake and played in the snow...yet I have PD. If vitamin D insufficiency truly has a role in many diseases, I hate to think what the future holds for the wii generation.

It is alarming to see so many affluent neighborhoods in the school district where I teach look like ghost Mcmansion villages; there are rarely any people outside on the front lawn, retrieving their mail; let alone kids playing street hockey, kickball, or even just riding a bike. There are never any children outside period. It is creepy. The prefab $700-800K homes that still have families do not even have sidewalks. They are all designed to be conveniently accessed by the expressway. What are we doing to ourselves?

I can't begin to tell you how many kids have off the chart allergies! All I know is a 4 inch binder is not big enough to hold all the allergen profiles I get for the kids we teach. The ironic thing is that these children are not born with so many allergies, rather their hyper vigilant, over protective parents induce them. The kids have no pets, no carpet fibers to contend with, no dirt under their nails, no skinned knees to band aid, and they don't spend any time out doors, so you can imagine the list of allergens stemming from this. They of course, all have nut allergies, but it extends now to include a vast array of tree nuts. Those with more severe allergies are required to don a fanny pack holding an epi pen the entire school day. I swear I wonder how they actually can manage to breathe when outdoors lest it bring on allergy attack. I shudder to think of the health problems they will face as adults and am almost certain there will be a fallout of major proportions from this insane lifestyle and parenting approach. Ironically, in their zeal to protect, they are instead laying the ground work for future auto-immune related health issues.

To these parents, I have two words "George Carlin" and his take on germs and the immune system...it needs practice. If you link to the video it is funny stuff but there is a language alert...don't click if you are easily offended by the F-bomb.

"When I was a kid the big scare was Polio, but me and my friends never got it. You know why? Because we swam in raw sewage..."

http://www.youtube.com/watch?v=CnmMNdiCz_s

-Laura
http://www.physorg.com/news/2010-11-people-sick.html
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Old 11-30-2010, 06:55 AM #74
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Shocked Here is a show stopper for you!

Look what appeared today!

http://news.yahoo.com/s/ap/20101130/...beat_vitamin_d

One could say poor methodology... Big Pharma lobbyists,
or whatever.

There are just so many papers saying the reverse! But you KNOW this one will get TV coverage and be everywhere.

I am going to continue with my 5,000 IU daily.
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Old 11-30-2010, 08:12 AM #75
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It is odd that no mention is made of the positive studies. And one would think that people all over America were wolfing down Vit D when it just isn't so. A mention of the value of monitoring serum levels instead of oral intake would have been a nice touch, too. Heck, maybe the stuff is good enough that someone sees a need to act proactively.

Quote:
Originally Posted by mrsD View Post
Look what appeared today!

http://news.yahoo.com/s/ap/20101130/...beat_vitamin_d

One could say poor methodology... Big Pharma lobbyists,
or whatever.

There are just so many papers saying the reverse! But you KNOW this one will get TV coverage and be everywhere.

I am going to continue with my 5,000 IU daily.
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Born in 1953, 1st symptoms and misdiagnosed as essential tremor in 1992. Dx with PD in 2000.
Currently (2011) taking 200/50 Sinemet CR 8 times a day + 10/100 Sinemet 3 times a day. Functional 90% of waking day but fragile. Failure at exercise but still trying. Constantly experimenting. Beta blocker and ACE inhibitor at present. Currently (01/2013) taking ldopa/carbadopa 200/50 CR six times a day + 10/100 form 3 times daily. Functional 90% of day. Update 04/2013: L/C 200/50 8x; Beta Blocker; ACE Inhib; Ginger; Turmeric; Creatine; Magnesium; Potassium. Doing well.
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Old 11-30-2010, 09:06 AM #76
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Default also involved is...

"I can't begin to tell you how many kids have off the chart allergies! All I know is a 4 inch binder is not big enough to hold all the allergen profiles I get for the kids we teach. The ironic thing is that these children are not born with so many allergies, rather their hyper vigilant, over protective parents induce them. The kids have no pets, no carpet fibers to contend with, no dirt under their nails, no skinned knees to band aid, and they don't spend any time out doors, so you can imagine the list of allergens stemming from this. They of course, all have nut allergies, but it extends now to include a vast array of tree nuts. Those with more severe allergies are required to don a fanny pack holding an epi pen the entire school day. I swear I wonder how they actually can manage to breathe when outdoors lest it bring on allergy attack. I shudder to think of the health problems they will face as adults and am almost certain there will be a fallout of major proportions from this insane lifestyle and parenting approach. Ironically, in their zeal to protect, they are instead laying the ground work for future auto-immune related health issues..."
-Laura[/QUOTE]

I personally believe we are and have been mucking up our immune systems bigtime with the increasing vaccine program. I got a few shots when young, today our kids are expected to get over 36 shots with 150 more "candidates" in the pipeline. Even the experts are beginning to get concerned that our body will not know what to do when confronted with a pathogen, as there is no way to innoculate us against every known, as well as unknown, pathogen out there.

I'm not against all vaccines, in fact, it's the rapid innoculation program at such a tender age with multiple vaccines in one shot that really concern me. Really, an 8lb baby, on average, getting the same amount of adjuvants, preservatives, and "fixtures" in his shot as a 150lb man? No way is that safe.

We didn't have all these allergies years ago, before this massive vaccine program really got going. Vaccines are a huge moneymaker and may well be viewed as the only way for pharmas to keep the huge profit margins going once more and more people realize that big pharma drugs really do not work all that well, especially over the long haul.
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Old 11-30-2010, 09:20 AM #77
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Lightbulb

There are many comments from medical scientists on the net, that believe the vaccines are to blame.

I agree with you!
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Old 11-30-2010, 03:39 PM #78
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Default Easiest D3

OK, today in my search for a good D3, I went to a little pharmacy that does compounding and carries stuff you can't get elsewhere...imagine my glee to discover a liquid D3 that you take with a dropper...brand is Xymogen and it's gluten free, soy free, yeast free, etc....contains sunflower oil which we all know is great for you.

The BEST part? ONE DROP (not dropperful, just one drop) has 1000IU in it! Five drops = 5000IU.

Another BEST part? The entire bottle of just over 2 ounces has 1500 drops in it and was about twenty bucks. So, if I did the math right and we take ten drops a day, give or take a few spilled drops for the shaky hand factor,we have five months worth of excellent quality D3 for about fifteen cents a day.
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Old 11-30-2010, 03:44 PM #79
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Lightbulb

That is great! There is a post about the drops on the D thread
on Vitamin forum.

I have some answers and links now on the main forum where
that Study appeared today:

http://neurotalk.psychcentral.com/thread139609.html

Some rebuttal comments are starting to show up.
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Old 11-30-2010, 03:47 PM #80
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Default Ugh is all I can say

Quote:
Originally Posted by mrsD View Post
Look what appeared today!

http://news.yahoo.com/s/ap/20101130/...beat_vitamin_d

One could say poor methodology... Big Pharma lobbyists,
or whatever.

There are just so many papers saying the reverse! But you KNOW this one will get TV coverage and be everywhere.

I am going to continue with my 5,000 IU daily.
I love how they utterly fail to mention you can get PLENTY of D3 from kale, which actually has more calcium in it, and better absorbed, than milk! Not to mention all those phyto properties of kale that are so good for us. Our government keeps pushing grains and dairy, grains and dairy, when paper after paper shows we do better eating veggies and fruits.

I doubt few folks reading that will realize the important thing is YOUR body's D3 levels, regardless of how much you have to take to get there. Someone may need to take 10,000IU to have a ng level of 60, someone else might only have to take 200IU. And BTW, I have several friends who have gone through breast cancer and all of them had low D3.

Again, ugh is all I can say.
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