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Old 02-14-2012, 12:17 PM #10
johnt johnt is offline
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johnt johnt is offline
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Join Date: Apr 2009
Location: Stafford, UK
Posts: 1,059
15 yr Member
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Wikipedia states that Tyrosine Hydroxylase "is increased acutely (minutes) by phosphorylation and chronically (days) by protein synthesis. ... The phosphorylation can be sustained by nicotine for up to 48 hours."

"Tyrosine hydroxylase or tyrosine 3-monooxygenase is the enzyme responsible for catalyzing the conversion of the amino acid L-tyrosine to dihydroxyphenylalanine (DOPA). . . . It does so using tetrahydrobiopterin as a coenzyme. DOPA is a precursor for dopamine, "

http://en.wikipedia.org/wiki/Tyrosine_hydroxylase

John
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Born 1955. Diagnosed PD 2005.
Meds 2010-Nov 2016: Stalevo(75 mg) x 4, ropinirole xl 16 mg, rasagiline 1 mg
Current meds: Stalevo(75 mg) x 5, ropinirole xl 8 mg, rasagiline 1 mg
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