Parkinson's Disease Tulip


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Old 03-07-2007, 08:46 AM #111
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Default Might as well take it to the next level

Quote:
PLEASE BE AWARE THAT THE FOLLOWING STORY IS VERY GRAPHIC AND HAS BEEN VERY DISTURBING TO SOME FORUM MEMBERS. IT WAS WRITTEN TO STIMULATE THE THOUGHT PROCESSES TO THE POINT THAT EACH INDIVIDUAL MIGHT RESEARCH THE ISSUE OF STEM CELL RESEARCH IN ORDER DISCOVER HOW HE/SHE FEELS ABOUT IT. IT WAS NEVER MY INTENTION TO CAUSE DEBATE, BUT DEBATE HAS BEGUN. IT WAS NEVER MY INTENTION TO CAUSE HURT, BUT FEELINGS HAVE BEEN HURT. ALL COMMENTS ARE WELCOME(PRO STEM CELL OR ANTI STEM CELL), BUT PLEASE REFRAIN FROM ATTACKING ANOTHER INDIVIDUAL. YOU ARE ALL VERY IMPORTANT. (edited to add the above at 4:32 est, Jan.31,2001)
michael


H.S. 1,208
(Pooper)

chapter 1


REPORTER: Hi. I�m Keith Porter from the Daily Times.

RECEPTIONIST: Yes, Mr. Porter, Dr. Stepholin is expecting you. Please, follow me, and I�ll take you to see him.
------------------
Porter follows the receptionist down a long corridor.
------------------
RECEPTIONIST: Dr. Stepholin, this is Mr. Keith Porter from the Daily Times. Mr. Porter, this is Dr. Stepholin, the chief administrator here at Ontogeny International.

DR. STEPHOLIN: Hello, Keith. Just call me Doc. I�ve been looking forward to this interview. I don�t know how you were selected for this exclusive, but you are one, lucky man. Thank you, Ms. Lorn. I�ll take it from here. Keith, let me show you around while you ask me any questions that you
have.

KEITH: Doc., I feel very privileged to be here. Do you mind if I use a
c.d. recorder during the interview so that I don�t have to take time out for
writing?

DR. STEPHOLIN: Of course you may, Keith. Now, ask away while we take a walk down to the lab section.

KEITH: I guess the first question is the obvious one. The name of this
company is Ontogeny International. For the record, what exactly is Ontogeny?

DR. STEPHOLIN: That is the perfect question to begin this interview, Keith.
I�ll give you a brief overview of what it is while we walk. It�s exact meaning will become more clear as we tour the labs. Ontogeny, the company, was birthed in the year 2002 after congress finally gave the go ahead for stem cell research. At first, the funding was skimpy, but we were able to tap into other government programs by establishing mock subsidiaries with various, appropriate names such as Hopeco, Ltd., F.A.C.T.,INC., which stands for Find a Cure Tomorrow, Inc., etceteras. We are a fully-government-funded, private company.

Our research involves studying all of the various aspects of cell development.
We start with a stem cell that we obtain from a discarded human fetus. Basically, a stem cell is a cell that has not yet been programmed to become a specialized cell, such as a skin cell or a bone cell. We isolate that stem cell and then we watch it and analyze it as it divides and differentiates. Unless we interrupt the differentiation, it usually follows a particular, predetermined pathway.

We watch as the cells are acted upon by gene expression which tells them to begin forming the mesoderm, the endoderm and the ectoderm. From these three cell types, all of the various cells, organs, tissues and systems of the human body are formed.

By observing and analyzing each step in the process, we have been able to understand all of the mechanisms involved in cell differentiation. As a result, we have been able to duplicate the processes. We can, at any given time during the process, insert the gene expression required for a particular cell type, and that cell type will then be produced. For example, we can now take any cell in the human body and cause it to differentiate into any cell we want. If we have a bone cell, we can coax it to produce a nerve cell. If we have a skin cell, we can persuade it to produce a bone cell.

Are you getting the picture here, Keith? Can you see how exciting this is? But, wait. That is only the beginning. By being able to direct gene expression at will, we have been able to create not only various cells, but we have also been able to create any tissue, organ or system that we choose. We have even been able to create an entire, intact spinal column with the spinal cord attached. Do you know what this means, Keith? It means that paraplegics and quadriplegics will now, instead of being confined to a wheelchair, be able to walk and function normally again.

KEITH: That is about the most exciting thing I have ever heard, Doc. How in the
world can you contain all of the excitement that you must feel?

But, Doc. I don�t understand something. When I arrived at the facility, there
were scores of people with signs, protesting. They were yelling things like, "Murderers,"" "Baby Killers," "God Wannabees," and "Their Blood Cries Out to God from the Earth." Don't they understand all of the good that is being done here? Don't they know how much suffering your work is going to eliminate from humanity? If you can do all that you say you can do, why, the potential is unlimited. What is their problem?

DR. STEPHOLIN: For the most part, they�re just a bunch of so-called Christians
who believe that there is a god somewhere out in space who put all of this together
intentionally. I guess they�re afraid that we and our work are going to kick their crutch out from under them and destroy their erroneous belief system. We just ignore them
and put up with the hassle. We�ve come too far to allow a bunch of cultists to ruin
our work.

Ah, here we are. This is the entrance to our pride and joy. Through these doors
lies the hope of tomorrow. We secretly call it the Gold Mine.(hahahahahaha)

End of Chapter 1


chapter 2

KEITH: I had no idea that this facility was this large. Why do you need all of this space, Doc.? I mean, cells are very small. They can't possibly take up this much space.

DR. STEPHOLIN: Oh, this is nothing. We have the same amount of space on the basement floor, and we have plans in the near future to add a second and a third floor.

Phase 1 of the project actually didn't take up that much space. Our facility consisted of one small room with a couple of tables, a computer, two microscopes, and various and sundry types of lab equipment. In Phase 1 we merely extracted a stem cell, gave it proper nutrition in a petri dish, and tried to keep it alive. When it died, we would just throw it away and begin again. Those were some very frustrating times.

KEITH: What happened to change all of that, Doc.? By the looks of things, you have obviously come a long way since the simple petri dish days. What do these doors lead to?

DR. STEPHOLIN: Oh, I�m glad you asked. Let�s go in, and I�ll take you on
the tour of your life. Are you ready?

KEITH: I�m ready if you are, Doc. Let the tour begin.
---------------
The doors open, and Keith Porter takes 2 steps into the huge, sterile looking
room. He stops. A cold chill runs down his spine as he stands frozen with
mouth open and eyes wide.
---------------

DR. STEPHOLIN: Well, Keith, what do you think? Is this impressive or what?
Let me show you around. Each of these clear vats represents one phase of cell
differentiation. Each vat has its own station with a controlled environment and a
full array of diagnostic instrumentation. The first station represents the beginning of
our latest endeavor. Each endeavor represent weeks or even months of trial and
error, and successes and failures. The station is not assembled here until the processes are completed and perfected. From each station, we monitor and analyze the
specimen. We presently have 1,208 stations established in this room. Are you impressed yet, Keith? Keith? Mr. Porter! Are you still with me?

KEITH: Huh? Oh, yeah, I'm still with you. I just didn't expect what I'm seeing here. It�s so big, so clinical, so cold.

I don't think I understand what I'm seeing. What about this first station?
All I see here is an empty vat.

DR. STEPHOLIN: Look more closely, Keith. Look toward the middle of
the vat. Do you see it?

KEITH: Oh, do you mean that small spot that looks like a ball? I guess I was expecting something else. How is this little ball going to be the hope of the future that you�ve been talking about?

DR.STEPHOLIN: hahahahaha. Just remember, the closest stations are just
beginning development. Let�s walk. The stations are arranged chronologically.
Some of them are not far enough along to analyze yet, so they are said to be in
the monitoring stage.

KEITH: Oh, wow, Doc., look at this one. It's really beginning to look like
something now. I think I'm beginning to see the picture.
-------------
Woah, Doc. What happened to number 583? I thought you said that they weren�t put out here until they were perfected? This one is missing a leg.

DR. STEPHOLIN: From this point on in the development, every tenth station is
used for analysis. The part that is being analyzed is removed from the specimen,
dissected, and scrutinized to make sure that everything is going as planned. Sometimes
that�s just the price we have to pay for perfection. Nothing worth having is obtained
without a price tag. Right, Keith?

KEITH: That�s what I've been told, Doc.
---------
Hey, Doc., did you see that one? It moved. It looked like it was trying to kick or something. I guess sometimes a nerve in these things gets stimulated, and a reflex action occurs. Is that right, Doc.? Biology was never my strong subject in school. hahahahaha.

DR. STEPHOLIN: Actually, Keith, that wasn't a reflex movement. That's just what
a fetus at this stage of development naturally does.

KEITH: What do you mean by fetus, Doc.? I thought that these were specimens.

DR. STEPHOLIN: Well, they are specimens, Keith, but what good would a dead
specimen be to us? We take great care to keep each specimen alive. That�s the only
way that we can actually see and analyze the ongoing development process. Remember,
I told you that every tenth specimen is designated to be analyzed, and this is achieved through the removal of the particular portion of the anatomy that is being studied.
-----------------
Keith Porter begins to feel ill as he gazes upon some of the most horrible sights his eyes have ever beheld. In every tenth vat exists a horror story in the process of being written. Each successive specimen
exhibits more signs of life than the previous one. He wants to run and find a place to throw up, but his feet seem to be frozen to the floor. They arrive in front of specimen 1,102.
-----------------
DR. STEPHOLIN: We're here, Keith. This is where the Gold Mine begins. Right here begins the harvesting phase.

KEITH: The what?

DR. STEPHOLIN: The harvesting phase. From the next 106 specimens we will harvest parts for use in repairing broken lives. We will end the suffering of so many people who would otherwise be destined to live a life of frustration and pain. We will give joy and fulfillment back to their lives. We will be able to provide, hearts, lungs, livers, arms, legs, spleens and any other part that you can name. Of course, we�ll be able to practically set any price we want; hence, "The Gold Mine."
-------------------
The playful, gurgling sound of a small infant interrupts their conversation.
-------------------
Ah, here is H.S. 1,208. This specimen is due to become the first donor. It is appropriate that the recipient will be one of our chief researchers, Dr. Redding.

KEITH: Dr. Redding?

DR. STEPHOLIN: Apparently he was trying to clean his pistol at home when he stopped
to jot down some notes on this very specimen. He had forgotten to unload the gun, and it went off. The bullet hit his heart. We found him in time to get him on life support. He was, I mean, he is, so dedicated. I would often hear him talking to the specimens in the same manner as someone who talks to their plants. He even gave them pet names. He was still clutching his notes when we found him The last note wasn�t quite finished. All it had on it was, " H.S. 1,208(Pooper) --eyes met--said dada." I guess we'll find out what he was trying to say tomorrow after he gets his new heart.

the end


The preceding story was entirely fictional. Any resemblance to actual facts, companies, people or situations is merely coincidental.
Moderators...If this is too graphic or if it does not pertain to this thread, please let me know, and I will remove it and provide a link to it instead. Thank you.

Here is the link Science or Science Fiction

[This message has been edited by michael7733 (edited January 26, 2001).]

[This message has been edited by michael7733 (edited January 31, 2001).]

Last edited by michael7733; 03-07-2007 at 09:05 AM. Reason: to add a hyperlink
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Old 03-07-2007, 09:03 AM #112
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Interesting bit of dystopian science fiction. But what does this have to do with the reality of embryonic stem cell research?
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Old 03-07-2007, 09:19 AM #113
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I think the relevancy is quite clear...of ccourse I could be wrong...I've been wrong before, and I'll be wrong many more times in my life. It gives basically the same information that several previous posts gave, but in a different manner. Perhaps I should go back and spend another 3 hours reading everything again to be sure.

michael b.
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Old 03-07-2007, 09:25 AM #114
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Quote:
Originally Posted by michael7733 View Post
I think the relevancy is quite clear...of ccourse I could be wrong...I've been wrong before, and I'll be wrong many more times in my life. It gives basically the same information that several previous posts gave, but in a different manner. Perhaps I should go back and spend another 3 hours reading everything again to be sure.

michael b.
I'm still not clear... are you intimating that allowing federal funding for ESCR will lead to fetus labs where experimental humans are grown in jars???

If that's the case, I could just as easily write a shock story about the horrors of "electricity" or "computers" or "the internal combustion engine" or "penecillin" or "open heart surgery" or "deep brain stimulation" or any OTHER advance in human knowledge and science.
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Old 03-07-2007, 09:53 AM #115
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Default Don't Miss The Point!

We can argue all we want - ANY chronic illness (whether it results in death - or we know the cause - or how disabling) is serious. It seriously deteriorates the quality of life that one should have.

If you want to pick this article apart for which disease is worse, whether or not to support stem cell research, or whatever, you can - but don't miss the point that was intended. It's the story of how Parkinson's has no socioeconomic, gender or race barriers. It's about knowing what's ahead if we don't find a cure or at least a way to slow this train down.

It's well written and ever so close too home.

Peggy

PS just for the record, I am a pro-life Bible belt evangelical who prayed and did lots of research, but I fully support the present propoosed legislation (S 3 Stem Cell Research Enhancement Act of 2007). I'll gladly discuss my views via private message or offline.
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Old 03-07-2007, 09:58 AM #116
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Quote:
Originally posted by michael7733:
The preceding story was entirely fictional. Any resemblance to actual facts, companies, people or situations is merely coincidental.
That means that it is up to the reader to differentiate the fact from the fiction. If any part of the story, though not true at the present, could in the future become a possibility, then perhaps, that possibility should be scrutinized as well as the present facts.

michael b.
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Old 03-07-2007, 10:31 AM #117
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Originally Posted by michael7733 View Post
That means that it is up to the reader to differentiate the fact from the fiction. If any part of the story, though not true at the present, could in the future become a possibility, then perhaps, that possibility should be scrutinized as well as the present facts.

michael b.
Sure. We could nitpick and ponder and worry and freeze ourselves into a state of perpetual fear over all kinds of silly things, and then NO research gets done. But hopefully cooler heads will prevail.

Thank goodness the people who developed the country's electric grid weren't paralyzed by fear and superstition. Same goes for the scientists who came up with transplant technology. And practically every other great scientific advance.
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Old 03-07-2007, 10:54 AM #118
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"To begin, let me say that stem cell research covers a lot of territory, and many methods or techniques are incorporated in pursuing an understanding of ontogeny.
I am not against stem cell research. I find it fascinating. I am, however, against the use of fetal tissue as a methodology of obtaining the stem cells for research.
Satan is usually subtle in the approach he uses to kill, steal and destroy, and man has proven himself to be no match against satan's subtleties. There was only one rule or guideline issued to man in the garden, and he ignored all of God's wonderful gifts in order to have what was not yet given to him. He showed his greed and desire to make his own rules there, and in the thousands of years of his existence, he has not gotten any better.

Without the rule of God in our lives, we are no different. Man would have already ended his own existence if not for God's presence. Should we assume that man will obey the guidelines established by other men concerning stem cell research any better than he obeyed God's rules? I don't think so. Two old sayings apply here: 1)Give him an inch, and he'll take a mile, and 2) Give him enough rope, and he'll hang himself.

Eventually, stem cell research will lead to cloning. First it will be just human cells, tissues and then organs. What will come later will be "complete" replicas of humans. I put complete in quotation marks, because I do not believe that the human soul can be duplicated by man. If my assumption is correct, then what will be produced? I will leave that one to your imagination.

During all of this emerges the aspect of cloning for monetary gain. What has man withheld from himself when it comes to monetary gain. He has broken every law in the book. Let's just take speed limits as an example. Whether the speed limit is 10 mph or 100 mph, man will exceed it and justify his excess by saying, "Oh the law allows us 5 mph to play with."

So, what am I saying? Although I am not against stem cell research in itself, I am aware of what devastation it will eventually bring. It will become another tower of Babel. Man, in his arrogance will play god, and he will eventually make man in his own image, but what about the living soul that comes from the breath of God?

It is my opinion that the best thing that man can do for himself is to look at cell ontogeny and come to the conclusion that we are fearfully and wonderfully made. We are the design of One Creator, and we are not Him. The beginning of wisdom is to fear God. We would all be better off if, instead of spending so much time and money trying to fix mankind that we have broken, we should begin to spend more time and money seeking ways not to break any more. God designed our bodies to heal themselves. No, I'm not saying that we should not try to cure man's diseases. Of course we should, but I think that we should choose other alternatives.

So, even though I am not against using stem cell research to understand the awesomeness of God's creation, I am against what it will lead to. I am doubly against the use of fetal tissue to carry on this research. With all of that said, I simply cannot and will not endorse stem cell research. However, it will happen with or without my endorsement.

In this forum, I have now stated my opinion on this subject as much as I care to. I won't even offer my opinion any more concerning the issue. I know that I said that one other time, but this time I'll try my best to say no more concerning this subject. It would just be a waste of time. I'll continue to try to offer peace and hope and God's love instead. Laughter goes a long way, too."

michael
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Old 03-07-2007, 11:03 AM #119
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I appreciate your comments, Michael. Sincerely.

You express your opinion very well. But it's opinion. Not fact.

For instance, your claim that mankind would have been destroyed long ago without God's presence. I submit that more people have been killed because of religion than any other reason.

But that's a different argument for a different forum on a different day.

However ... as do most who point to their interpretation of "God's word" in this argument ... you seem to think that your view of religion should be the law of the land as far as medical research is concerned.

I believe in a just and loving God. And I believe God imbues us with wisdom and knowledge.

And, like I told Vicky, in my ever-so-humble opinion, Satan dances with delight when we suffer, and would love nothing BETTER than for us to continue suffering this affliction when the cure might just be a couple years of research away.

Where we part company is here... you seem to believe blastocysts are "babies." I say they are not. Best medical evidence says they are not.

And again, the question remains...

If you're against ESCR, why are you not ALSO vigorously combatting IVF?
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Old 03-07-2007, 11:07 AM #120
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Default Thank you Michael

A brave post. I haven`t to date said which way I would go.
HOWEVER...
this might be fiction...but if this is what it takes in order for me to be healthy,then no....emphatically no...I would rather cut my own leg off and experiment on that.A baby farm,for spares....uh uh....does not sit comfortably with me.

Having said that I still back scientific research performed within ethical ground rules. And still hold true to my belief that those ethics should be evident in all of us,regardless of colour or creed.

I guess we ALL need ALL the information.Every tiny little bit of information... No stone unturned.

Thank you again Michael,for this .
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