Is Restless Leg Syndrome Real or a Means to Peddle DA Agonists s FDA approval?

dopadoc · 04-13-2011, 03:23 PM

What's even more interesting is that another pharmaceutical "super-off-label-good-for-everything-from-bipolar-to-nonspecific-pain"...aka:yesterday's "Neurontin"...carbamazepine, is implicated in another iatrogenic mess. Non-mistake-related drug reactions have been estimated to be at the cause of twice the number of deaths in the US than those from automobiles. That's roughly 3 9/11's a month.
MD MD

mrsD · 04-13-2011, 03:42 PM

Back in the "old days" (early 70's) we used to "joke" that Geigy drugs were all toxic. Phenylbutazone was a fast mover...before NSAIDs were developed. Tegretol was hardly used at all back then. Mostly for Trigeminal Neuralgia and 3rd line for seizures. Times have sure changed. (and Geigy is gone and incorporated into Ciba)

No longer in US for humans, but does find its way into Chinese products and herbs for arthritis now and then illegally here.

Bob Dawson · 04-13-2011, 04:12 PM

Quote:

Originally Posted by mrsD

What I think is the most egregious off label use today is Seroquel (a potent antipsychotic with terrible side effects) being pushed to internists and GPs for patients with simple insomnia!

oh yeah I did not make the connection that MrsD made, but you know my fight with sleep deprivation; LOTS of people being fed anti-psycho drugs and treated as crazy when what they needed was sleep. I mean, you end up in a ward of people all being drugged and no one believes you no matter what you say because they would not be giving you those drugs if you weren't crazy and if you complain they figure you need a higher dosage.

What we really need is a high-class opium den, genre Cairo in 1850

olsen · 04-13-2011, 04:44 PM

I continue to think our best hope is to nationalize the pharmaceutical industry. and I am not for Big Government. Just think the government could not do any worse and at least we can pretend the government has to answer to the citizens.

Jomar · 04-15-2011, 02:15 PM

Quote:

Originally Posted by mrsD

Restless leg symptoms also come from low iron status, and poor magnesium intake.

But there are some hard core patients who have it still when those things are fixed.

I'll have to up my magnesium, I've been having minor bouts of RLS.

Dad w/PD has upped his Mirapex for RLS sx per his Dr.
( I thought he was totally off of it

) but his main issue is dozing off randomly when home & quiet in the house.

olsen · 04-16-2011, 07:23 AM

at times my husband is unable to tolerate oral magnesium (cannot discern the reason). at those times he uses a topical form of magneium oil. it's a guess how much he is getting though there are levels noted on the label. it seems to help him; it certainly helps with my leg cramping (I am a caretaker, not a patient)

paula_w · 04-16-2011, 07:47 PM

Several years back I had a neighbor who had severe restless leg syndrome and a severe immune deficiency. Although I didn't know her there, she was living in Hawaii and drank the pesticide contaminated milk that I did. Not only did it do the above to her, while she was taking mirapex for RLS, she developed a gambling habit online - would spend up to $400 a week. She does not have pd, but a host of other problems.

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