She is allergic to sinemet suddenly and we just found out. I'll pass this on most def. b/c she's doing horribly. Apparently it ulcerates her esophagus. Thanks so much for mentioning this. It had not occurred to me.

Hello Dogma,

The inside of my mouth, esophagus, tongue are irritated and often bleed because of the Sinemet. Also, about 30 mins. to an hour after taking it, I start coughing up "stuff".
The pharmacist told me to take a Benadryl, and if it helped, then I would know I was allergic. Well, it helped. Although, I wasn't supposed to take Benadryl because I also take Selegiline. So, if she doesn't take an MAO inhibitor, and if she is able to take Benadryl, that would be a good test.
I'm still trying to find a pharmacy who can get the Mylan brand of Sinemet.

Sometimes, I think the adverse effects and side effects of these PD drugs are not worth loosening up, being relieved of the pain, and getting about more quickly.

Glad I could help, even though it was an accident.

Tonya

Sometimes the best things happen by accident. I'm forwarding this link to my mom and X'ing fingers. BIG thanks.