From www.*******.com:

27th April 2011 - New research

INTESTINAL BACTERIA IS HIGHLY PREVALENT IN PARKINSON'S DISEASE

Movement Disorders [2011] 26 (5) : 889-892 (Gabrielli M, Bonazzi P, Scarpellini E, Bendia E, Lauritano EC, Fasano A, Ceravolo MG, Capecci M, Rita Bentivoglio A, Provinciali L, Tonali PA, Gasbarrini A.) Complete abstract

Small intestinal bacterial overgrowth has been found to be highly prevalent in Parkinson's Disease. Parkinson's Disease is associated with gastrointestinal motility abnormalities that could favour the occurrence of small intestinal bacterial overgrowth. The aim of this study was to assess the prevalence of small intestinal bacterial overgrowth in people with Parkinson's Disease. The prevalence of small intestinal bacterial overgrowth was far higher in people with Parkinson's Disease. It occurred in over half (54%) of all people with Parkinson's Disease, in contrast to only 8% of people that do not have Parkinson's Disease. The severity of Parkinson's Disease was also very significantly related to small intestinal bacterial overgrowth.

This can lead to the following symptoms : excess gas, abdominal bloating and distension, abdominal pain, and diarrhea or in some cases chronic constipation. For more information go to Small intestinal bacterial overgrowth. The researchers suggest that the gastrointestinal motility abnormalities that often occur in Parkinson's Disease might explain this association. In order to refer to this article on its own click here.

If your sinemet doesn't seem to work as well, could be your small intestine (where it is absorbed) is laden with bacteria that are interfering. Someone here posted an article that h. pylori colony size actually increases with sinemet, kind of like a tape worm grows bigger when you eat. Sick analogy, I know, sorry.

Edit: not sure why it won't let me list the website but it's *******.
Yep, it deleted it again. Anyone knows, let me know.

Try this one-
http://www.ncbi.nlm.nih.gov/pubmed/21520278

I suspect that you were attempting to link to a site that is blocked due to some past unpleasantness but I'm not sure.

Actually no, but it looks like the data is the same. The site I was reading is spelled with a v, then an i, then an a, then an r, then a t, then another i, then an s. Let's see if this gets kicked out too!

It is run by a notorious troll who so disrupted this forum that the moderators were forced to ban him. I suspect that you have bumped into a part of the protective barrier.

http://www.eurekalert.org/pub_releas...-ubm051811.php

I just had to drag in Dragon to answer this post'

Some of you may know me as a stage V PWP and co-author of " the book"
sometimes I characterize myself as a white rat in late stage. Rick will remember me as the guy with Parkinson's partial paralysis also known as pope's paralysis.

Within the past 24 hours I was diagnosed with a second bacterial infection of the small intestine and am being treated with two antibacterial drugs. I have experienced several of the symptoms mentioned in the article including severe constipation, nausea and excessive gas. Assuming that qualifies me as a white rat I will keep forum members advised of treatment results. Stay tuned! Bob C

I swear, what a find in the research dept.! I am continually impressed by the research skills of the people on this forum. Seriously, from obscure herbs to unheard-of lab work to recipes for tinctures and fermented foods, so much can be found right here on this forum.

I'm not a gambler, but I'd be willing to bet not a one of our neuros has ever heard of any involvement or inter-relation between H. Pylori and PD. I'm actually excited about the next appt. so I can bring a copy of this to discuss!

We've been talking about HP here for four or five years. It seemed that no one was listening, but maybe they just didn't want to share the credit.

Do you suppose that we should tell them that one of the most effective controls of H pylori is turmeric/curcumin?

In fairness to the world of neuro's Braak et al were discussed at the WPC, though I did not attend that session, so am not sure what conclusions were drawn. I believe that Braak's hypothesis includes some of this stuff. Rick, correct me if I am wrong. However, to think that this stuff is part of mainstream thinking would be to stretch a point.........

Interestingly one of the reasons that the duodopa pump treatment works so well is because of dopamine uptake in the gut....... it gets it to the right place.

Not quite the same topic, but it is related.......

Lindy