FAQ/Help |
Calendar |
Search |
Today's Posts |
05-26-2011, 01:07 PM | #1 | |||
|
||||
Senior Member
|
Genetic Risk Factor for Parkinson’s Linked to Increased Alpha-Synuclein
http://www.pdf.org/en/science_news/r.../?CMP=EMC-NEWS - Apr 20 2011 Researchers have shed light on a mystery about the relationship between a gene called GBA and Parkinson’s disease (PD). Carriers of mutations in this gene are at a higher risk for Parkinson’s for unknown reasons. Researchers found that mutations in the gene lead to an accumulation of alpha-synuclein protein in brain cells, the hallmark of the disease. The research was published in the April 6 online edition of Annals of Neurology... ...mutations in a gene known as glucocerebrosidase or GBA, are the most common genetic risk factor for Parkinson’s. People who carry mutations in one copy of the GBA gene may have up to a five times the normal risk of developing PD. In addition, mutations in GBA increase the risk of another neurodegenerative disease, dementia with Lewy bodies (DLB). Mutations in both copies of a person’s GBA gene cause the rare disorder known as Gaucher’s disease. But the role of this gene in the development of Parkinson’s remained unknown.
__________________
In the last analysis, we see only what we are ready to see, what we have been taught to see. We eliminate and ignore everything that is not a part of our prejudices. ~ Jean-Martin Charcot The future is already here — it's just not very evenly distributed. William Gibson |
|||
Reply With Quote |
Reply |
|
|
Similar Threads | ||||
Thread | Forum | |||
Increased Melanoma Risk in Parkinson Disease | Parkinson's Disease | |||
new genetic finding of PD zeroes in on alpha synuclein | Parkinson's Disease | |||
Alpha synuclein news | Parkinson's Disease | |||
Curcumin inhibits alpha-synuclein | Parkinson's Disease |