Parkinson's Disease Tulip


advertisement
Reply
 
Thread Tools Display Modes
Old 08-11-2011, 01:42 PM #1
reverett123's Avatar
reverett123 reverett123 is offline
In Remembrance
 
Join Date: Aug 2006
Posts: 3,772
15 yr Member
reverett123 reverett123 is offline
In Remembrance
reverett123's Avatar
 
Join Date: Aug 2006
Posts: 3,772
15 yr Member
Default So riddle me this...

Epinephrine (aka adrenaline) is made from dopamine.

Because epinephrine is involved in the fight or flight response, it would seem reasonable that if overall dopamine supplies run low, then epinephrine production has priority.

If we have hypervigilant personalities and spend our lives with an increased need for epinephrine, then we are more likely to experience a chronic or recurring shortage of dopamine, the raw material for the epinephrine.

If we have a metabolic problem that limits the amount of dopamine we are capable of turning out, won't our lives and personalities reflect this chronic shortage of this important neurotransmitter, perhaps even generating the "Parkinson's personality"?

Since production of epinephrine/adrenaline worsens the shortage of dopamine, won't we learn early in life to suppress feelings, avoid emotions, etc in order to balance out as best we can?

Finally, while it is by no means certain that the death of neurons in the SN are cause rather than victim, what would be the net result on these neurons if they were forced to strain to function with this constant problem? Would they eventually die?
__________________
Born in 1953, 1st symptoms and misdiagnosed as essential tremor in 1992. Dx with PD in 2000.
Currently (2011) taking 200/50 Sinemet CR 8 times a day + 10/100 Sinemet 3 times a day. Functional 90% of waking day but fragile. Failure at exercise but still trying. Constantly experimenting. Beta blocker and ACE inhibitor at present. Currently (01/2013) taking ldopa/carbadopa 200/50 CR six times a day + 10/100 form 3 times daily. Functional 90% of day. Update 04/2013: L/C 200/50 8x; Beta Blocker; ACE Inhib; Ginger; Turmeric; Creatine; Magnesium; Potassium. Doing well.
reverett123 is offline   Reply With QuoteReply With Quote
"Thanks for this!" says:
anon72219 (08-11-2011)

advertisement
Old 08-11-2011, 03:12 PM #2
paula_w paula_w is offline
In Remembrance
 
Join Date: Aug 2006
Location: Florida
Posts: 3,904
15 yr Member
paula_w paula_w is offline
In Remembrance
 
Join Date: Aug 2006
Location: Florida
Posts: 3,904
15 yr Member
Default agree agree

Quote:
Originally Posted by reverett123 View Post
Epinephrine (aka adrenaline) is made from dopamine.

Because epinephrine is involved in the fight or flight response, it would seem reasonable that if overall dopamine supplies run low, then epinephrine production has priority.

If we have hypervigilant personalities and spend our lives with an increased need for epinephrine, then we are more likely to experience a chronic or recurring shortage of dopamine, the raw material for the epinephrine.

If we have a metabolic problem that limits the amount of dopamine we are capable of turning out, won't our lives and personalities reflect this chronic shortage of this important neurotransmitter, perhaps even generating the "Parkinson's personality"?

Since production of epinephrine/adrenaline worsens the shortage of dopamine, won't we learn early in life to suppress feelings, avoid emotions, etc in order to balance out as best we can?

Finally, while it is by no means certain that the death of neurons in the SN are cause rather than victim, what would be the net result on these neurons if they were forced to strain to function with this constant problem? Would they eventually die?


i agree that everything you said is a strong possibility and it also explains how it could lead to eventual detachment, aloofness, capacity to feel anything. like when i was in a minor car accident, my stomach didn't even feel fear. but i have a ton of anxiety.

i was always considered to be aloof and i didn't hug people till i started meeting pwp. i didn't even like to be touched ...felt that was in my space ..used to think i was '"tactile defensive."

well actually i was

paula
__________________
paula

"Time is not neutral for those who have pd or for those who will get it."
paula_w is offline   Reply With QuoteReply With Quote
Old 08-11-2011, 03:21 PM #3
paula_w paula_w is offline
In Remembrance
 
Join Date: Aug 2006
Location: Florida
Posts: 3,904
15 yr Member
paula_w paula_w is offline
In Remembrance
 
Join Date: Aug 2006
Location: Florida
Posts: 3,904
15 yr Member
Default chicken or the egg

and yes i also believe that emotion suppression and family stress could start with epinephrine suppressing dopamine production.

adding because now i am thinking....as a teacher i could not take my problems to school. i had to be on, pleasant ,even entertaining, patient, etc. then home to two girls and multiple activities. stress, anxiety have been with me forever it seems.
__________________
paula

"Time is not neutral for those who have pd or for those who will get it."
paula_w is offline   Reply With QuoteReply With Quote
Reply

Thread Tools
Display Modes

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off


Similar Threads
Thread Thread Starter Forum Replies Last Post
Riddle Time SallyC The Stumble Inn 3 04-04-2011 11:53 AM
Out on a limb: Arm-swinging riddle is answered GregD Parkinson's Disease 1 07-29-2009 05:21 PM
Today's riddle. oldsteve On the Lighter Side 1 06-20-2009 03:19 PM
riddle me this? jennyk38 Reflex Sympathetic Dystrophy (RSD and CRPS) 7 06-08-2007 08:57 PM
A Riddle Braindrain On the Lighter Side 1 09-27-2006 11:27 AM


All times are GMT -5. The time now is 05:29 AM.

Powered by vBulletin • Copyright ©2000 - 2024, Jelsoft Enterprises Ltd.

vBulletin Optimisation provided by vB Optimise v2.7.1 (Lite) - vBulletin Mods & Addons Copyright © 2024 DragonByte Technologies Ltd.
 

NeuroTalk Forums

Helping support those with neurological and related conditions.

 

The material on this site is for informational purposes only,
and is not a substitute for medical advice, diagnosis or treatment
provided by a qualified health care provider.


Always consult your doctor before trying anything you read here.