If the surgery you are having precludes taking anything by mouth for a significant time, you can make liquid Sinemet which can be sipped as needed or put down a stomach tube (taken off of suction for 30 min). The total daily dose is mixed in a small amount of warm water containing 2 grams of ascorbic acid powder (vitamin C). Then enough water is added to make one liter. It is taken in divided doses during the next 24 hours.

Good morning, Paula,
I am looking out my window; the leaves have all changed colour; what was left of the garden got frozen last week - very late this year. It is amazing that we were still eating from the garden, almost to mid-October.
Ursula and I are thinking about you, and about suing the pickle ball empire, and about meeting you when the world P.D. congress is in Montreal.

Hi Bob,

I woke up at 3 am and laid there till 6 am before getting meds. Never felt any pd symptoms....wondering why. My crooked hand is straightened and morning dystonia gone. when sinemet kicks in i see fingers on both hands contracting and it's bye bye mouth. sinemet kicking in appears visually like a stroke [not that i've ever had one - i think????] but all those good things, like, movement, verbalization and thinking come from sinemet kicking in. Peripherally it's a stroke.
[my words] i am in a fog and hoping i'm going to make it all the way home. the rehab center is on "my side" now. Ultimate paranoia.. .... i've got a major incision going and didn't think to ask for pain killers. today i did and got two percocets, so i''m wondering if i should still take 2 xanax and nortriptyline. i am the only one paying attention.


Thank you so much for asking. i would love to meet you and that lovely wife of yours and the funny guy.

pickle ball is a good guy.

Sasha

Sounds

Atma Namaste -

Was there more to the sentence? I would be really interested!

Thanks!

Sasha

Hi again,

Sasha, not sure if anyone answered you, but yes I did at one time take meds over night. This was my first inkling of addiction. I think that when your brain wakes you up at the same time every night every two-three hours at wear off times and you cannot get back to sleep without it...that tells you something. My next step was to see doctor about lowering my agonist dosage and that helped me immensely. A sleeping pill that is time release may help but they leave me too brain foggy in AM. Natural things you can try are melatonin or brain entrainment waves (they correspond to our brain states of activity (alpha beta, theta delta) to induce sleep. I plan to try this wave stuf very soon.

Wanted to share this reply by Mark Combes from the the PDF forums . Mark is a pharmacist who also happens to have PD.

This is Mark the pharmacist I run the "ask the Pharmacist" forum. Or is true that even sinemet at high enough doses can cause an addictive/obsessive issues.It is all based on the amount of dopamine in the system.
A good example is this. You have an empty glass, which represents the maximum amount of dopamine you need. The glass is set on a table, the table represents the "feel good" receptors. The water you pour into the glass is dopamine. Once you reach the top, your symptoms are taken care of. Once the water (dopamine) overflows, it hits the "feel good" receptors and cause the feel food seeking behavior. Everyones glass is a different size but, it doesn't matter the source of dopamine that fills the glass. The dopamine agonists have been targeted because they are the quickest at building up (or filling up) the glass. It takes higher doses and a longer time for sinemet, but YES, it can happen.

Hope this clarifies the matter.