FAQ/Help |
Calendar |
Search |
Today's Posts |
11-06-2011, 10:53 AM | #1 | |||
|
||||
Member
|
Study phase II.
A drug normally used for diabetes, called Pioglitazone, is to undergo clinical trials in people with early Parkinson’s Disease. The aim is to determine whether it can slow clinical decline over a 44 week period. Pioglitazone is being given in 15mg and 45 mg dosages. Pioglitazone is an FDA approved drug for the treatment of diabetes. It has not been previously studied in people with Parkinson's Disease. Pioglitazone is marketed in tablet form as Actoplus, Duetact, and Actos. It acts primarily by decreasing insulin resistance. Neither source for the clinical trials provides a rationale for the use of Pioglitazone in Parkinson's Disease. Insulin resistance has never been shown to cause Parkinson's Disease. Preliminary studies have been carried out using Pioglitazone on animals concerning Parkinson's Disease. However, the circumstances of those studies are not comparable with idiopathic Parkinson's Disease in humans. http://clinicaltrials.gov/ct2/show/NCT01280123 http://www.pdtrials.org/en/browse/all/view/317
__________________
Sim00 Born in 1969, diagnosed PD in 2007, first symptoms 2004. DBS in July 2016. |
|||
Reply With Quote |
|
|
Similar Threads | ||||
Thread | Forum | |||
Trophos Reaches Mid-Point of Phase II Clinical Trial of TRO19622 in Painful Diabetic | ALS News & Research | |||
December 2007 • Clinical Trial Information for the Parkinson's Community | Parkinson's Disease | |||
My Experience in a Parkinson’s Clinical Trial...by JeanB | Parkinson's Disease | |||
CLINICAL TRIAL: Improve Speech Using an In-the-Ear Device in Parkinson's Disease | Parkinson's Disease Clinical Trials | |||
3 pts in obese diabetic drug trial developed MS | Multiple Sclerosis |