http://www.healthcanal.com/mental-he...s-disease.html

From the paper referenced:

"[Possibly] the effects of neurodegeneration can be counteracted to some extent by introducing more noise in the CNS." [1]

"Noisy sensory signals can be transmitted to the CNS through any sensory pathway, ..." [1]

Has anyone tried a noisy (irregular pulses) TENS machine?

[1] "Noisy Galvanic Vestibular Stimulation Promotes GABA Release in the Substantia Nigra and Improves Locomotion in Hemiparkinsonian Rats"
Ghazaleh Samoudi, Hans Nissbrandt, Mayank B. Dutia and Filip Bergquist
http://www2.sahlgrenska.gu.se/pressimages/brus.pdf

John

no
neurologix is/was implanting a gaba gene in the brain in phase1/phase2 but a different area

There have been a number of reports of PWP exhibiting synchronous firing of blocks of neurons. Too much order. You have to have a little chaos in the system. Kind of the way a radio transmits using a highly ordered carrier wave as a baseline with a data laden broadcast wave paired with it.

We talk about music helping us function by providing a rhythmic beat that we can move to. Maybe we have it backwards and the music actually helps by partially overcoming the excessive order that is so characteristic of PD?

More on the same theme.

Although still in its early days, with testing being done on rats, a paper by Bergquist [1] is very interesting. The diagrams are superb.

"Low extracellular dopamine levels produce insufficent neural noise – this
impairs signal transmission/system function.
Adding moderate noise to a low noise system will improve neural functions, if it is not optimal to begin with."

"Stochastic vestibular stimulation
• Non invasive.
• Low amplitude (<1 mA) currents selectively activates vestibular
afferents.
• By using a noisy stimulation pattern, the vestibular system is
activated without inducing the sensation of movement (vertigo)."

[1] "The effect of sensory noise on basal ganglia function in hypodopaminergic conditions"
Filip Bergquist, MD, PhD
Dept of Neurology, Sahlgrenska University Hospital, Gothenburg Sweden
Dept of Pharmacology, University of Gothenburg,
www.dsls.usra.edu/20111118.pdf

John

How could someone rig something like this up at home? We already have a TENS unit...could we just attach the thing to our head, and if so, where?