Parkinson's Disease Tulip


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Old 01-09-2012, 05:22 PM #1
paula_w paula_w is offline
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paula_w paula_w is offline
In Remembrance
 
Join Date: Aug 2006
Location: Florida
Posts: 3,904
15 yr Member
Default Do we need biomarkers for placebo effect?

if there are gains that are merely Head Games and placebo effect, aren't there things we should control in forming the groups and keep them as similar as possible? The participants have to be different in some ways after treatment.

Point: gdnf was not followed up to learn the long term effects. that question was asked in the NPR audio.


New trial design ....it's so overdue.Thanks for the link Linda. What can we think about in finding ways to identify them short of asking the surgeons? What signs are present in those who only have the real thing?
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Old 01-09-2012, 05:43 PM #2
paula_w paula_w is offline
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paula_w paula_w is offline
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Default cognition comes into control

after almost 3 mos, of rehab and now home alone, i finally understand why cognition is so connected to gait and balance. the plain trurh is we just get to the point where multi'tasking isn't just a loss. It becomes a danger. I have to talk myself out of freezing and i can do that. but not while talking on the phone.


this is when parkinson's is beginning to score some serious points in the game. I get up and go to aqauzumba\ and can keep up with our crazy instructor without getting out of breath; it and physical therapy are saving me.

I think cognition should be similar in trial groups for starters. A multi tasker could easily suspect he/she has the medicine instead of the lady with the broken leg and a walker. But looks are deceiving.

so much we could talk about but it has to be REAL SCIENCE. no five changes for phase II,

i am no longer a multi tasker when on my feet. all thought goes into walking without festination. freezing and pitching forward. the leg is still mending tho so i am aiming for walking without the walker.
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