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Methylcobalamin: A Potential Breakthrough in Neurological Disease

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Old 05-10-2013, 11:05 AM #31
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Default more on nitrous oxide
To further complicate things I just heard this am that sun exposure helps lower blood pressure because it causes our bodies to create NO.
Vita D on the one hand and NO on the other


Quote:
Originally Posted by lindylanka View Post
Sorry Laura, i did not realise you had posted a question to me. I am not basing my conjecture on the mention of B12 post-pregnancy, though there are many mentions on sites dealing with B12 deficiency that pregnancy can be a drain on reserves, especially in the case of vegetarian and vegan people. Rather I was referring to people over the years who mentioned that they developed PD within a few years of having a child. I am one of those, my son was under 4 when I got the first symptoms. If anyone has done any work on this specifically, I would be really interested to read it. :-)
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Old 05-10-2013, 04:25 PM #32
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Default I am impressed
Over the last two weeks and while taking Jarrow's Methyl B-12 at a dose of 15,000 mcg per day, I have reduced my daily intake of LD/CD from 2200 - 2400 mg with problematic performance to approx 1800 daily with no off periods other than the initial first of the morning butt-dragging episode. Very impressed.
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Born in 1953, 1st symptoms and misdiagnosed as essential tremor in 1992. Dx with PD in 2000.
Currently (2011) taking 200/50 Sinemet CR 8 times a day + 10/100 Sinemet 3 times a day. Functional 90% of waking day but fragile. Failure at exercise but still trying. Constantly experimenting. Beta blocker and ACE inhibitor at present. Currently (01/2013) taking ldopa/carbadopa 200/50 CR six times a day + 10/100 form 3 times daily. Functional 90% of day. Update 04/2013: L/C 200/50 8x; Beta Blocker; ACE Inhib; Ginger; Turmeric; Creatine; Magnesium; Potassium. Doing well.
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Old 05-10-2013, 06:01 PM #33
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Default rick, did you try 5,000mcg?
why 15,000?
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Old 05-10-2013, 06:39 PM #34
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Quote:
Originally Posted by soccertese View Post
why 15,000?
Somewhat due to reading the various postings in MrsD's threads and, in part, due to the fact that it was water soluble. Very much seat of the pants but it seemed that the risk was worth it and I did not want to fall short of some threshold without ever knowing that I had done so. -Rick
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Born in 1953, 1st symptoms and misdiagnosed as essential tremor in 1992. Dx with PD in 2000.
Currently (2011) taking 200/50 Sinemet CR 8 times a day + 10/100 Sinemet 3 times a day. Functional 90% of waking day but fragile. Failure at exercise but still trying. Constantly experimenting. Beta blocker and ACE inhibitor at present. Currently (01/2013) taking ldopa/carbadopa 200/50 CR six times a day + 10/100 form 3 times daily. Functional 90% of day. Update 04/2013: L/C 200/50 8x; Beta Blocker; ACE Inhib; Ginger; Turmeric; Creatine; Magnesium; Potassium. Doing well.
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Old 05-10-2013, 08:44 PM #35
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Default Hi madamlash
I don't have PD, but PN or RSD in ankle. I have been on B12 injections for over a year now. There is improvement. I was low, and listened to Mrs.D about getting it checked out. Thanks for your post. ginnie
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Old 05-13-2013, 03:22 AM #36
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Default
Rick what you have done is similar to how doctors treat b12 deficiency, with what they call loading doses. Lots initally to get you going then back down. If a person has a long standing deficiency this doesn't work so well. My guess is that as PwP we are well on the road to understanding how to manage medications, and given half a chance I would self medicate with B12, but am needle-phobic, and don't have the right cells to absorb it. Sub0linguals are maybe a way forward.

Always interested in anyone dealing with this and PD, its is a double whammy.
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