NeuroTalk Support Groups - Do people with tremor dominant PD respond to different meds than people with stiffne

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- - Do people with tremor dominant PD respond to different meds than people with stiffne (https://www.neurotalk.org/parkinson-s-disease/164855-people-tremor-dominant-pd-respond-meds-people-stiffne.html)

My friend had a hand and leg tremor even with meds...she tried fava sprout balls and the tremor stopped. As for the recipe...check four acres to grow favas Post. Personally..a really firm stretch as far as the arm will go can stop the restlessness and if the arm has come up into puppy begging position. (grab wrist of the problem hand with your other hand and stretch it to the other side shoulder level til tight and HOLD...crossing over to the other side of the body may have something to do with it) Worth a try . In church, I just sit on my hand if it bothers me or do a gentle stretch across my legs and down toward the seat. I don't usually notice tremors unless sitting for longer than 15 minutes...and it's hard to catch me in a 15 minute sit!

Which Beta Blocker?

For those of you who are tremor dominant--what beta blocker do you use to help with tremor? Or any other med that helps control tremor? It seems that there is almost nothing that is successful against tremor, at least from what I read and research. :confused: I started out with resting, then postural, more recently action.

20 milligrams of Inderal (propranolol). Helps if the tremor is stress or adrenaline induced.

Jon

Aquario, thanks for the info. Have you or anyone else who is tremor dominant tried Isradipine?

Talked with a doctor who was willing to write an rx, but my blood pressure has been so consistently low-normal (110 over 60) that I didn't want to lower it further. But if you give it a go please let me know the results.

Here's a link to a MJFox Foundation story.

https://www.michaeljfox.org/foundati...afe-Parkinsons

Jon

Thanks Aquario. I spent some time on the mjff website and saw they might need participants for a phase 3 isradipine clinical trial and will look further into that. Will let you know if and when I start taking isradipine.:)

tremor dominant PD

Hey all you fellow movers and shakers. I am not tremor dominant, bradykinesia and rigidity are my constant companions. I have had DBS and wonder how many of you have looked into it. The results are far,far better for tremor than any other symptom. They can target the leads right to where they need to be in order for them to be effective. I have had PD for 15 yrs. now and I'm on sinemet 25/100 1 tablet every 2 hours. Agonists only raise the chance of dyskinesia. I have tried benadryl with good results but the other people on the road won't stay home so I can get out. :eek: Couldn't stay awake!
I guess its the old story of write down all your problems then exchange papers with someone and you'll want your paper back!

Response to different meds?

I got to thinking about this and it would be kind of obvious to me that as someone who takes the sinemet (carbidopa/levodopa) in order to move otherwise I get rigid. So I would reason that no it would not be effective in reducing tremors since it enables movement, as opposed to slowing it. The DBS interrupts the signals that are too excited and cause the tremor. Just my thoughts. I would not think that the carbidopa is very effective, any input? Maybe someone who has a tremor AND rigidity?

Quote:

Originally Posted by Jim091866 (Post 952522)

Jim, I often wonder the same thing. Your problem, from what you indicated, is you can't get out of your chair due to rigidity, whereas mine is I can't stay in the chair due to tremors. So I would guess the same med you take to enable movement wouldn't necessarily do me any good because I need to diminish movement. They almost seem like two separate diseases with the need for two separate therapies. BTW, I can take 38 mg of benadryl and notice only slight slowing of my tremors and with no drowsiness. Prior to all this PD mess, you could have knocked me out with 25 mg of benadryl....go figure.:confused:

The Parkinson's Disease Foundation pdf.org has a regular posting of science news that will be of interest to most on this list.

Read PDF’s take on a study which found different brain activity in people living with Parkin
son’s who experience tremors versus those who do not have tremors:
http://www.pdf.org/en/science_news/r.../pr_1361899345

I'm finding this distinction in many sources.