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03-10-2012, 08:57 AM | #8 | |||
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Imad,
As I understand, the remaining few healthy dopaminergic neurons can't keep up with the need for dopamine because the first and second reactions which produce tyrosine and DOPA are rate-limiting, or slower. However, as long as there are some neurons still functioning, they can convert exogenous l-DOPA to dopamine by that faster final reaction. |
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"Thanks for this!" says: | Conductor71 (03-10-2012) |
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