 |
|
Parkinson's Disease  |
| View Poll Results: Did you lose (a noticeable level of)your sense of smell before Parkinson's diagnosis? | ||||||
| Yes |
   
|
5 | 55.56% | |||
|
||||||
| No |
  
|
4 | 44.44% | |||
|
||||||
| Voters: 9. You may not vote on this poll | ||||||
| Reply |
|
|
Thread Tools | Display Modes |
04-11-2012, 11:46 AM
|
#1 | ||
|
|||
|
Junior Member
|
Some research indicates that the loss of dopaminergic neurons can first present as a loss of smell and this can possibly be an early warning sign in the progression of Parkinson's.
Please let us know whether you sensed a diminishing ability to smell before your Parkinson's was diagnosed. |
||
|
 Reply With Quote
|
|
04-11-2012, 09:39 PM
|
#2 | |||
|
||||
|
Senior Member
|
There is an official scratch and sniff test developed at the U of Pennsylvania. If anyone is curious or unsure, you can order a test online. It is purported to be 90% accurate in diagnosing Parkinson's. What does that mean for those of us who retain our sense of smell? The author's of this article make a strong case that our clinical diagnostic criteria be expanded or improved on by looking at things beyond the "cardinal signs". They point out that...
Is Parkinson's disease a primary olfactory disorder? Viewed alone the UPSIT result places 81% of patients outside the 95% limit for controls. When this information is combined with OEP data (4/10 abnormal where UPSIT score was normal) the fraction of olfactory abnormality approaches 90%. Such frequency is higher than that of tremor, which is usually quoted at 70%16 and nearly equals that of rigidity and akinesia. At least for a hospital population, olfactory dysfunction is common and potentially as important as the cardinal motor signs of PD. A final point to consider is what we mean by a disease. The frequency of the three cardinal signs of PD is not well established, and was addressed only by Hoehn and Yahr at a time when parkinsonian syndromes were less well appreciated. No single sign is pathognomic of PD. Defective smell sense is found in about 80% of IPD classified clinically. What if there were patients with tremor, rigidity and akinesia, of whom 80% were blind? Would this be classified as movement or visual disorder? If the blindness came first the disease would probably be classified as a visual disorder and it would then be proposed that the condition was a visual problem with motor accompaniments. If blindness is replaced by anosmia, the analogy is complete. The most disabling symptoms and signs (and indeed the initial symptoms and signs) do not necessarily equate with the primary causative mechanism. |
|||
|
|
Reply With Quote
|
|
04-11-2012, 09:48 PM
|
#3 | |||
|
||||
|
Senior Member
|
I started losing my sense of smell 20 years before my parkinson's dx. I had thought it was due to allergies. I was wrong.
Jean |
|||
|
|
Reply With Quote
|
|
04-12-2012, 11:34 AM
|
#4 | ||
|
|||
|
Member
|
I started to notice a weakened sense of smell about 8 - 10 years before the diagnosis. But I do have a very narrow nostril in one side and it constantly causes blockage. ENT doctors told me this may affect my sense of smell and they suggest a surgery. But I believe now PD is also the cause...
|
||
|
|
Reply With Quote
|
| Reply |
|
|
Similar Threads
|
||||
| Thread | Forum | |||
| Study to Test if Fading Sense of Smell Signals Onset of Parkinson's | Parkinson's Disease Clinical Trials | |||
| Study to Test if Fading Sense of Smell Signals Onset of Parkinson's | Parkinson's Disease | |||
| PCB'S and Our Sense of Smell | Parkinson's Disease | |||
| sense of smell | Multiple Sclerosis | |||
Did your sense of smell weaken before onset of Parkinson's?
lost sense of smell
Linear Mode
